C
Christian Drouet
Researcher at University of Grenoble
Publications - 112
Citations - 4948
Christian Drouet is an academic researcher from University of Grenoble. The author has contributed to research in topics: Hereditary angioedema & Angioedema. The author has an hindex of 34, co-authored 108 publications receiving 4465 citations. Previous affiliations of Christian Drouet include Ludwig Institute for Cancer Research & Paris Descartes University.
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Journal ArticleDOI
Hereditary and acquired angioedema: problems and progress: proceedings of the third C1 esterase inhibitor deficiency workshop and beyond.
Angelo Agostoni,Emel Aygören-Pürsün,Karen Binkley,Alvaro Blanch,Konrad Bork,Laurence Bouillet,Christoph Bucher,Anthony J. Castaldo,Marco Cicardi,Alvin E. Davis,Caterina De Carolis,Christian Drouet,Christiane Duponchel,Henriette Farkas,Kalman Fay,Béla Fekete,Bettina Fischer,Luigi Fontana,George Füst,Roberto Giacomelli,Albrecht Gröner,C. Erik Hack,George Harmat,John Jakenfelds,Mathias Juers,Lajos Kalmar,Pál Novák Kaposi,István Karádi,Arianna Kitzinger,Tímea Kollár,Wolfhart Kreuz,Peter L. Lakatos,Hilary Longhurst,Margarita López-Trascasa,Inmaculada Martinez-Saguer,Nicole Monnier,István Nagy,Éva Németh,Erik Waage Nielsen,Jan H. Nuijens,Caroline O'Grady,Emanuela Pappalardo,Vincenzo Penna,Carlo Perricone,Roberto Perricone,Ursula Rauch,Olga Roche,E. Rusicke,Peter J. Späth,George Szendei,Edit Takács,Attila Tordai,Lennart Truedsson,Lilian Varga,Beáta Visy,Kayla Williams,Andrea Zanichelli,Lorenza C. Zingale +57 more
TL;DR: This supplement contains work presented at the third workshop and expanded content toward a definitive picture of angioedema in the absence of allergy, and includes cumulative genetic investigations; multinational laboratory diagnosis recommendations; current pathogenesis hypotheses; and suggested prophylaxis and acute attack treatment.
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Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation
M. Kathryn Liszewski,Martin Kolev,Gaelle Le Friec,Marilyn K. Leung,Paula Bertram,Antonella F. Fara,Marta Subias,Matthew C. Pickering,Christian Drouet,Seppo Meri,T. Petteri Arstila,Pirkka T. Pekkarinen,Margaret H. Y. Ma,Margaret H. Y. Ma,Andrew P. Cope,Andrew P. Cope,Thomas Reinheckel,Santiago Rodríguez de Córdoba,Behdad Afzali,Behdad Afzali,John P. Atkinson,Claudia Kemper +21 more
TL;DR: It was found that the T cell-expressed protease cathepsin L (CTSL) processed C3 into biologically active C3a and C3b, which was observed in all examined cell populations, suggesting that intracellular complement activation might be of broad physiological significance.
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In situ apoptotic cell labeling by the TUNEL method: improvement and evaluation on cell preparations.
A. Negoescu,Philippe Lorimier,Françoise Labat-Moleur,Christian Drouet,Catherine Robert,Christiane Guillermet,Christian Brambilla,Elisabeth Brambilla +7 more
TL;DR: The results showed that with an adequate pretreatment, reliable TUNEL can be obtained after each fixative tested, and the existence of a limited population of intensely TUNel-positive cells that lacked apoptotic morphology contributes to the current debate about a preapoptotic state.
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Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III
Sven Cichon,Ludovic Martin,Hans Christian Hennies,Felicitas Müller,Karen Van Driessche,A. Karpushova,Wim J. Stevens,Roberto Colombo,Thomas Renné,Christian Drouet,Konrad Bork,Markus M. Nöthen +11 more
TL;DR: It is concluded that enhanced FXII enzymatic plasma activity in female mutation carriers leads to enhanced kinin production, which results in angioedema.
Journal Article
Enhancers and transcription factors controlling the inducibility of the tumor necrosis factor-alpha promoter in primary macrophages.
TL;DR: Compelling evidence is provided for the role of transcription factors belonging to the NF-kappa B/rel family in the activation of the TNF-alpha promoter.