C
Christiane Werner-Favre
Researcher at Geneva College
Publications - 19
Citations - 2014
Christiane Werner-Favre is an academic researcher from Geneva College. The author has contributed to research in topics: CD40 & B cell. The author has an hindex of 13, co-authored 19 publications receiving 1946 citations.
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BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.
Pascal Schneider,Fabienne Mackay,Véronique Steiner,Kay Hofmann,Jean Luc Bodmer,Nils Holler,Christine Ambrose,Pornsri Lawton,Sarah A. Bixler,Hans Acha-Orbea,Danila Valmori,Pedro Romero,Christiane Werner-Favre,Rudolph H. Zubler,Jeffrey L. Browning,Jürg Tschopp +15 more
TL;DR: A novel member of the T NF family, designated BAFF (for B cell activating factor belonging to the TNF family), which is expressed by T cells and dendritic cells is described, suggesting that BAFF plays an important role as costimulator of B cell proliferation and function.
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Limiting dilution assay for human B cells based on their activation by mutant EL4 thymoma cells: total and anti‐malaria responder B cell frequencies
Li Wen,Mattana Hanvanich,Christiane Werner-Favre,Nicolette Brouwers,Luc Perrin,Rudolf H. Zubler +5 more
TL;DR: A culture system that leads to activation, proliferation and differentiation into antibody‐secreting cells (ASC) of about 90% of B cells from peripheral blood or spleen is reported on.
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Efficient transduction of primary human B lymphocytes and nondividing myeloma B cells with HIV-1–derived lentiviral vectors
Fabrice Bovia,Patrick Salmon,Thomas Matthes,Krisztian Kvell,Tuan H. Nguyen,Christiane Werner-Favre,Marc Barnet,Monika Nagy,Florence Leuba,Jean-François Arrighi,Vincent Piguet,Didier Trono,Rudolf H. Zubler +12 more
TL;DR: HIV vectors are promising tools for studies of gene functions in primary human B cells and myeloma cells for the purposes of research and the development of gene therapies.
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Cell surface antigen CD5 is a marker for activated human B cells.
TL;DR: In the present study, CD5‐ B cells were isolated by cell sorter and then stimulated in vitro with mutagenized EL4 thymoma cells in the presence of T cell supernatant and the CD5 antigen behaves as a B cell activation marker.
Journal ArticleDOI
Cytokine mRNA expression during an in vitro response of human B lymphocytes: kinetics of B cell tumor necrosis factor alpha, interleukin (IL)6, IL-10, and transforming growth factor beta 1 mRNAs.
Thomas Matthes,Christiane Werner-Favre,Huayang Tang,Xiaohong Zhang,Vincent Kindler,Rudolf H. Zubler +5 more
TL;DR: Findings show a differentiation stage-related cytokine program during a B cell response, whereby B cells can become activated without IL-1 alpha or IL- 1 beta expression, and mRNA for positive (IL-10) and negative (TGF-beta 1) autoregulatory factors coexists in cell populations during the later phase of the response.