C
Christine E. MacBrayne
Researcher at Boston Children's Hospital
Publications - 36
Citations - 479
Christine E. MacBrayne is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Antibiotics. The author has an hindex of 9, co-authored 28 publications receiving 321 citations. Previous affiliations of Christine E. MacBrayne include University of Colorado Boulder & University of Montana.
Papers
More filters
Journal ArticleDOI
Multicenter Initial Guidance on Use of Antivirals for Children With Coronavirus Disease 2019/Severe Acute Respiratory Syndrome Coronavirus 2.
Kathleen Chiotos,Molly Hayes,David W. Kimberlin,Sarah B. Jones,Scott H. James,Swetha G. Pinninti,April Yarbrough,Mark J. Abzug,Christine E. MacBrayne,Vijaya L. Soma,Daniel E. Dulek,Surabhi B Vora,Alpana Waghmare,Alpana Waghmare,Joshua Wolf,Rosemary Olivero,Steven P. Grapentine,Rachel L. Wattier,Laura Bio,Shane J Cross,Nicholas O Dillman,Kevin J. Downes,Kathryn Timberlake,Jennifer L. Young,Rachel C Orscheln,Pranita D. Tamma,Hayden T. Schwenk,Philip Zachariah,Margaret L. Aldrich,David L. Goldman,Helen E. Groves,Gabriella S Lamb,Alison C Tribble,Adam L. Hersh,Emily A. Thorell,Mark R. Denison,Adam J. Ratner,Jason G. Newland,Mari M. Nakamura +38 more
TL;DR: Antiviral therapy for COVID-19 is not necessary for the great majority of pediatric patients, but for those rare children who develop severe or critical disease, this guidance offer an approach for decision-making regarding antivirals, informed by available data.
Journal ArticleDOI
Initial Guidance on Use of Monoclonal Antibody Therapy for Treatment of Coronavirus Disease 2019 in Children and Adolescents.
Joshua Wolf,Mark J. Abzug,Rachel L. Wattier,Paul K. Sue,Surabhi B Vora,Surabhi B Vora,Philip Zachariah,Daniel E. Dulek,Alpana Waghmare,Alpana Waghmare,Alpana Waghmare,Rosemary Olivero,Kevin J. Downes,Scott H. James,Swetha G. Pinninti,April Yarbrough,Margaret L. Aldrich,Christine E. MacBrayne,Vijaya L. Soma,Steven P. Grapentine,Carlos R. Oliveira,Molly Hayes,David W. Kimberlin,Sarah B. Jones,Laura Bio,Theodore H. Morton,Jane S. Hankins,Gabriela Maron,Kathryn Timberlake,Jennifer L. Young,Rachel C Orscheln,Hayden T. Schwenk,David L. Goldman,Helen E. Groves,W. Charles Huskins,Nipunie S Rajapakse,Gabriella S Lamb,Alison C Tribble,Elizabeth C Lloyd,Adam L. Hersh,Emily A. Thorell,Adam J. Ratner,Kathleen Chiotos,Mari M. Nakamura +43 more
TL;DR: In this article, a panel of experts in pediatric infectious diseases, pediatric infectious disease pharmacy, pediatric intensive care medicine, and pediatric hematology from 29 geographically diverse North American institutions was convened.
Journal ArticleDOI
Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1-Infected Individuals: SWIFT-C.
Susanna Naggie,Kristen M. Marks,Michael Hughes,Daniel S. Fierer,Christine E. MacBrayne,Arthur Y. Kim,Kimberly Hollabaugh,Jhoanna Roa,Bill Symonds,Diana M. Brainard,John G. McHutchison,Marion G. Peters,Jennifer J. Kiser,Raymond T. Chung +13 more
TL;DR: Sofosbuvir-ribavirin for 12 weeks for the treatment of acute HCV genotype-1 infection in HIV-1-infected persons results in a high relapse rate.
Journal ArticleDOI
Sustainability of Handshake Stewardship: Extending a Hand Is Effective Years Later
Christine E. MacBrayne,Manon C. Williams,Claire Levek,Jason Child,Kelly Pearce,Meghan Birkholz,Jim Todd,Amanda L. Hurst,Sarah K. Parker +8 more
TL;DR: The handshake method is an effective and sustainable approach to stewardship and has no detrimental effects on severity adjusted mortality, readmissions, or lengths of stay.
Journal ArticleDOI
Development and validation of a dried blood spot assay for the quantification of ribavirin using liquid chromatography coupled to mass spectrometry
Leah C. Jimmerson,Jia-Hua Zheng,Lane R. Bushman,Christine E. MacBrayne,Peter L. Anderson,Jennifer J. Kiser +5 more
TL;DR: Development and validation of a reversed-phase high performance liquid chromatographic (LC), tandem mass spectrometry (MS/MS) assay for the determination of ribavirin (RBV) in DBS demonstrates that DBS can be used as an alternative to plasma for PK-PD studies in human subjects.