C
Chuan Hong
Researcher at Harvard University
Publications - 74
Citations - 1121
Chuan Hong is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 12, co-authored 51 publications receiving 486 citations. Previous affiliations of Chuan Hong include VA Boston Healthcare System & University of Pittsburgh.
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Journal ArticleDOI
Empirical Comparison of Publication Bias Tests in Meta-Analysis
TL;DR: Given the relatively low agreement between many publication bias tests, meta-analysts should not rely on a single test and may apply multiple tests with various assumptions.
Journal ArticleDOI
High-Throughput Phenotyping With Electronic Medical Record Data Using a Common Semi-Supervised Approach (PheCAP)
Yichi Zhang,Tianrun Cai,Sheng Yu,Kelly Cho,Kelly Cho,Chuan Hong,Jiehuan Sun,Jie Huang,Yuk-Lam Ho,Ashwin N. Ananthakrishnan,Zongqi Xia,Stanley Y. Shaw,Vivian S. Gainer,Victor M. Castro,Nicholas Link,Jacqueline Honerlaw,Sicong Huang,David R. Gagnon,David R. Gagnon,Elizabeth W. Karlson,Robert M. Plenge,Peter Szolovits,Guergana Savova,Susanne Churchill,Christopher J. O'Donnell,Shawn N. Murphy,Shawn N. Murphy,J. Michael Gaziano,J. Michael Gaziano,Isaac S. Kohane,Tianxi Cai,Katherine P. Liao,Katherine P. Liao,Katherine P. Liao +33 more
TL;DR: PheCAP takes structured data and narrative notes from electronic medical records and enables patients with a particular clinical phenotype to be identified, and includes a phenotype algorithm, the probability of the phenotype for all patients, and a phenotype classification.
Journal ArticleDOI
Association of interleukin 6 receptor variant with cardiovascular disease effects of interleukin 6 receptor blocking therapy: A phenome - Wide association study
Tianxi Cai,Tianxi Cai,Yichi Zhang,Yichi Zhang,Yuk Lam Ho,Nicholas Link,Jiehuan Sun,Jiehuan Sun,Jie Huang,Jie Huang,Tianrun Cai,Tianrun Cai,Scott M. Damrauer,Yuri Ahuja,Jacqueline Honerlaw,Lauren Costa,Petra Schubert,Chuan Hong,David R. Gagnon,David R. Gagnon,Yan V. Sun,Yan V. Sun,J. Michael Gaziano,J. Michael Gaziano,Peter W.F. Wilson,Kelly Cho,Kelly Cho,Kelly Cho,Philip S. Tsao,Philip S. Tsao,Christopher J. O'Donnell,Christopher J. O'Donnell,Christopher J. O'Donnell,Katherine P. Liao,Katherine P. Liao,Michael Gaziano,Rachel Ramoni,Jim Breeling,Kyong-Mi Chang,Grant D. Huang,Sumitra Muralidhar,Philip S. Tsao,Jennifer Moser,Stacey B. Whitbourne,Jessica V. Brewer,Jessica V. Brewer,John Concato,Stuart R. Warren,Dean P. Argyres,Brady Stephens,Mary Brophy,Donald E. Humphries,Nhan Do,Shahpoor Shayan,Xuan-Mai T. Nguyen,Saiju Pyarajan,Elizabeth R. Hauser,Hongyu Zhao,Rachel McArdle,Louis J. Dell’Italia,John B. Harley,Jeff Whittle,Jean C. Beckham,John M. Wells,Salvador Gutierrez,Gretchen Gibson,Laurence Kaminsky,Gerardo Villareal,Junzhe Xu,Mark B. Hamner,Kathlyn Sue Haddock,Sujata Bhushan,Pran Iruvanti,Michael Godschalk,Zuhair Ballas,Malcolm Buford,Stephen Mastorides,Jon B. Klein,Nora R. Ratcliffe,Hermes Florez,Alan Swann,Maureen Murdoch,P. S. Sriram,Scott Kinlay,Shing Shing Yeh,Ronald G Washburn,D Jhala,Samuel M. Aguayo,David M. Cohen,Satish C. Sharma,John J. Callaghan,Krisann K. Oursler,Mary A. Whooley,Sunil K. Ahuja,Amparo Gutierrez,Ron B. Schifman,Jennifer Greco,Michael Rauchman,Richard J. Servatius,Mary E. Oehlert,Agnes Wallbom,Ronald Fernando,Timothy R. Morgan,Todd Stapley,Scott Sherman,Gwenevere Anderson,Elif Sonel,Edward Boyko,Laurence Meyer,Samir Gupta,Joseph Fayad,Adriana M. Hung,Jack H. Lichy,Robin A. Hurley,Brooks Robey,Rob Striker +115 more
TL;DR: The findings of an association of theIL6R SNP with reduced risk for aortic aneurysms correspond with the newest indication for IL6R blockade, giant cell arteritis, of which a major complication is aorto-aneurysm.
Journal ArticleDOI
High-throughput multimodal automated phenotyping (MAP) with application to PheWAS.
Katherine P. Liao,Katherine P. Liao,Katherine P. Liao,Jiehuan Sun,Jiehuan Sun,Tianrun Cai,Tianrun Cai,Tianrun Cai,Nicholas Link,Chuan Hong,Chuan Hong,Jie Huang,Jennifer E. Huffman,Jessica L. Gronsbell,Yichi Zhang,Yichi Zhang,Yuk Lam Ho,Victor M. Castro,Vivian S. Gainer,Shawn N. Murphy,Shawn N. Murphy,Christopher J. O'Donnell,Christopher J. O'Donnell,J. Michael Gaziano,J. Michael Gaziano,J. Michael Gaziano,Kelly Cho,Kelly Cho,Kelly Cho,Peter Szolovits,Isaac S. Kohane,Sheng Yu,Tianxi Cai,Tianxi Cai +33 more
TL;DR: The multimodal automated phenotyping (MAP) algorithm increased the accuracy of phenotype definition while maintaining scalability, thereby facilitating use in studies requiring large-scale phenotypes, such as PheWAS.
Journal ArticleDOI
Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms.
April Jorge,Victor M. Castro,April Barnado,Vivian S. Gainer,Chuan Hong,Tianxi Cai,Tianrun Cai,Robert J. Carroll,Joshua C. Denny,Leslie J. Crofford,Karen H. Costenbader,Katherine P. Liao,Elizabeth W. Karlson,Candace H. Feldman +13 more
TL;DR: In this article, the authors used machine learning to generate data-driven SLE EHR algorithms and assessed performance of existing rule-based SLE algorithms and concluded that the machine learning algorithms performed well in internal and external validation.