Chung-Chou H. Chang

TL;DR: Investigating whether HIV is associated with an increased risk of acute myocardial infarction after adjustment for all standard Framingham risk factors among a large cohort of HIV-positive and demographically and behaviorally similar uninfected veterans in care found infections with HIV are associated with a 50% increased risk beyond that explained by recognized risk factors.

TL;DR: In this retrospective analysis of data sets from patients with sepsis, 4 clinical phenotypes were identified that correlated with host-response patterns and clinical outcomes, and simulations suggested these phenotypes may help in understanding heterogeneity of treatment effects.

TL;DR: Hospitalization for pneumonia was associated with increased short-term and long-term risk of CVD, suggesting that pneumonia may be a risk factor for CVD.

TL;DR: Among critically ill patients and their surrogates, a family‐support intervention delivered by the interprofessional ICU team did not significantly affect the surrogate's burden of psychological symptoms, but the surrogates' ratings of the quality of communication and the patient‐ and family‐centeredness of care were better and the length of stay in the ICU was shorter with the intervention than with usual care.

TL;DR: The provision of procalcitonin assay results, along with instructions on their interpretation, to emergency department and hospital‐based clinicians did not result in less use of antibiotics than did usual care among patients with suspected lower respiratory tract infection.