C
Claire Gaveriaux-Ruff
Researcher at University of Strasbourg
Publications - 57
Citations - 4811
Claire Gaveriaux-Ruff is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Opioid & Receptor. The author has an hindex of 27, co-authored 53 publications receiving 4290 citations. Previous affiliations of Claire Gaveriaux-Ruff include French Institute of Health and Medical Research.
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The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.
TL;DR: A random primed expression cDNA library was constructed from the RNA of NG 108-15 cells that encodes a 371-amino acid-residue protein presenting all the structural characteristics of receptors that interact with guanine nucleotide-binding proteins.
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Exploring the opioid system by gene knockout.
TL;DR: Data confirm and define a role for several genes of the opioid system in responses to other drugs of abuse, and the triple opioid receptor knockout mutant allows exploring non-classical opioid pharmacology.
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Opioid-induced hyperalgesia: Cellular and molecular mechanisms.
TL;DR: The molecular actors identified include the Toll-like receptor 4 and the anti-opioid systems as well as some other excitatory molecules, receptors, channels, chemokines, pro-inflammatory cytokines or lipids, which contribute to OIH.
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The delta opioid receptor: an evolving target for the treatment of brain disorders
TL;DR: The recent demonstration of biased agonism at the delta opioid receptor in vivo opens novel perspectives towards targeting specific therapeutic effects through drug design.
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Knockin mice expressing fluorescent δ-opioid receptors uncover G protein-coupled receptor dynamics in vivo
Grégory Scherrer,Petra Tryoen-Tóth,Dominique Filliol,Audrey Matifas,Delphine Laustriat,Yu Q. Cao,Allan I. Basbaum,Andrée Dierich,Jean Luc Vonesh,Claire Gaveriaux-Ruff,Brigitte L. Kieffer +10 more
TL;DR: Enhanced GFP (EGFP) is used to achieve functional imaging of a G protein-coupled receptor (GPCR) in vivo and revealed detailed receptor neuroanatomy throughout the nervous system of knock-in mice.