C
Clarence J. Gibbs
Researcher at National Institutes of Health
Publications - 118
Citations - 7121
Clarence J. Gibbs is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Virus & Kuru. The author has an hindex of 43, co-authored 118 publications receiving 7027 citations. Previous affiliations of Clarence J. Gibbs include Yeshiva University & California Institute of Technology.
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Journal ArticleDOI
Experimental Transmission of a Kuru-like Syndrome to Chimpanzees
Journal ArticleDOI
The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies.
TL;DR: In patients with dementia, a positive immunoassay for the 14-3-3 brain protein in cerebrospinal fluid strongly supports a diagnosis of Creutzfeldt-Jakob disease, but this finding does not support the use of the test in patients without clinically evident dementia.
Journal ArticleDOI
Infection of chimpanzees by human T-lymphotropic retroviruses in brain and other tissues from AIDS patients.
D. Carleton Gajdusek,Clarence J. Gibbs,Pamela Rodgers-Johnson,Herbert L. Amyx,David M. Asher,Leon G. Epstein,Prem S. Sarin,Robert C. Gallo,Annette E. Maluish,Larry O. Arthur,Luc Montagnier,Donna Mildvan +11 more
TL;DR: Findings confirm the active and persistent virus infection of chimpanzees with retroviruses derived from AIDS patients and establish the presence of viruses in the plasma and brain of AIDS patients by direct transmission of their virus to chimpanzees.
Journal ArticleDOI
Evidence for widespread infection of wild rats with hepatitis E virus in the United States.
Yamina Kabrane-Lazizi,Joshua B. Fine,Joe L. Elm,Gregory E. Glass,Harry Higa,Arwind Diwan,Clarence J. Gibbs,Xiang-Jin Meng,Suzanne U. Emerson,Robert H. Purcell +9 more
TL;DR: Rats from urban as well as rural areas were seropositive and the prevalence of anti-HEV IgG increased in parallel with the estimated age of the rats, leading to speculation that they might be involved in the puzzling high prevalence of the virus among some U.S. city dwellers.
Journal ArticleDOI
Phenotypic variability of Gerstmann-Straussler-Scheinker disease is associated with prion protein heterogeneity
Pedro Piccardo,Stephen R. Dlouhy,Patricia M.-J. Lievens,Katherine Young,Thomas D. Bird,David Nochlin,Dennis W. Dickson,Harry V. Vinters,T. R. Zimmerman,Ian R. A. Mackenzie,Stephen J. Kish,Lee Cyn Ang,Charles De Carli,Maurizio Pocchiari,Paul Brown,Clarence J. Gibbs,D. Carlton Gajdusek,Orso Bugiani,James W. Ironside,Fabrizio Tagliavini,Bernardino Ghetti +20 more
TL;DR: GSS is characterized by the presence PrP isoforms that can be partially cleaved to low molecular weight PrPres peptides, which suggests that spongiform changes in GSS are related to the presence of high levels of these distinct 21-30 kDa isoforms.