C
Claudia Jakubzick
Researcher at Dartmouth College
Publications - 88
Citations - 12902
Claudia Jakubzick is an academic researcher from Dartmouth College. The author has contributed to research in topics: Antigen & Macrophage. The author has an hindex of 42, co-authored 79 publications receiving 11045 citations. Previous affiliations of Claudia Jakubzick include Pennsylvania State University & University of Colorado Denver.
Papers
More filters
Journal ArticleDOI
Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in chronic granulomatous disease
Ruby Fernandez-Boyanapalli,S. Courtney Frasch,Stacey M. Thomas,Kenneth C. Malcolm,Michael Nicks,Ronald J. Harbeck,Claudia Jakubzick,Raphael A. Nemenoff,Peter M. Henson,Steven M. Holland,Donna L. Bratton +10 more
TL;DR: The data support the hypothesis that signaling from the NADPH oxidase under normal circumstances governs phagocytes mtROS production and that such signaling is lacking in the absence of a functioning phagocyte oxidase.
Journal ArticleDOI
Pulmonary dendritic cell development and antigen acquisition
TL;DR: Elucidating DC functions, particularly in the lung, may then allow use of the inherent ability of these cells for enhanced vaccine strategies and therapeutics for pulmonary infections and diseases.
Journal ArticleDOI
Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia.
Esther S. Choi,Claudia Jakubzick,Kristin J. Carpenter,Steven L. Kunkel,Holly L. Evanoff,Fernando J. Martinez,Kevin R. Flaherty,Galen B. Toews,Thomas V. Colby,Ella A. Kazerooni,Barry H. Gross,William D. Travis,Cory M. Hogaboam +12 more
TL;DR: The data suggest that CCL7 is highly expressed in biopsies and pulmonary fibroblast lines obtained from patients with UIP relative to patients with other IIP and patients without IIP, and that this CC chemokine may have a major role in the progression of fibrosis in this IIP patient group.
Journal ArticleDOI
Improving the Quality and Reproducibility of Flow Cytometry in the Lung. An Official American Thoracic Society Workshop Report.
Robert M. Tighe,Elizabeth F. Redente,Elizabeth F. Redente,Yen-Rei A. Yu,Susanne Herold,Anne I. Sperling,Jeffrey L. Curtis,Ryan Duggan,Suchitra Swaminathan,Hideki Nakano,William J. Zacharias,William J. Zacharias,William J. Janssen,Christine M. Freeman,Ryan R. Brinkman,Benjamin D. Singer,Claudia Jakubzick,Alexander V. Misharin +17 more
TL;DR: Given the importance of flow cytometry in pulmonary research, the American Thoracic Society convened a working group to highlight issues and technical challenges to the performance of high-quality pulmonaryFlow cytometry, with a goal of improving its quality and reproducibility.
Journal ArticleDOI
Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes.
Sonia M. Leach,Sophie L. Gibbings,Anita Tewari,Shaikh M. Atif,Brian Vestal,Thomas Danhorn,William J. Janssen,Tor D. Wager,Claudia Jakubzick,Claudia Jakubzick +9 more
TL;DR: This cross-species expression compendium serves as a resource for future translational studies to investigate beforehand whether pursuing specific MP subtypes or genes will prove fruitful, and only 13%–23% of the top 1,000 marker genes overlap in corresponding human-mouse MP counterparts.