R
Raphael A. Nemenoff
Researcher at Anschutz Medical Campus
Publications - 209
Citations - 11599
Raphael A. Nemenoff is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 59, co-authored 192 publications receiving 10391 citations. Previous affiliations of Raphael A. Nemenoff include University of Colorado Denver & Cornell University.
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Journal ArticleDOI
Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.
Raphael A. Nemenoff,Sim Winitz,Nan Xin Qian,Vicki Van Putten,Gary L. Johnson,Lynn E. Heasley +5 more
TL;DR: It is reported here that human cPLA2 is phosphorylated in vitro by two growth factor-stimulated serine/threonine-specific kinases, p42 MAP kinase and protein kinase C (PKC).
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Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation
Eric L. Campbell,Walter J. Bruyninckx,Caleb J. Kelly,Louise E. Glover,Eóin N. McNamee,Brittelle E. Bowers,Amanda J. Bayless,Melanie Scully,Bejan Saeedi,Lucy Golden-Mason,Stefan F. Ehrentraut,Valerie F. Curtis,Adrianne Burgess,John F. Garvey,Amber Sorensen,Raphael A. Nemenoff,Paul Jedlicka,Cormac T. Taylor,Douglas J. Kominsky,Sean P. Colgan +19 more
TL;DR: In this paper, the authors investigated the contribution of neutrophils and respiratory burst to inflammatory hypoxia and effective inflammatory resolution in a colitis model using HIF-inducible factor (HIF) mice.
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Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Expression Is Decreased in Pulmonary Hypertension and Affects Endothelial Cell Growth
Shingo Ameshima,Heiko Golpon,Carlyne D. Cool,Daniel Chan,R. William Vandivier,Shyra J. Gardai,Marilee J. Wick,Raphael A. Nemenoff,Mark W. Geraci,Norbert F. Voelkel +9 more
TL;DR: It is concluded that fluid shear stress decreases the expression of PPAR&ggr; in endothelial cells and that loss of PPARI; expression characterizes an abnormal, proliferating, apoptosis-resistant endothelial cell phenotype.
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Analysis of Orthologous Gene Expression between Human Pulmonary Adenocarcinoma and a Carcinogen-Induced Murine Model
Robert Stearman,Lori D. Dwyer-Nield,Laura K. Zerbe,Stacy A. Blaine,Zeng Chan,Paul A. Bunn,Gary L. Johnson,Fred R. Hirsch,Daniel T. Merrick,Wilbur A. Franklin,Anna E. Barón,Robert L. Keith,Raphael A. Nemenoff,Alvin M. Malkinson,Mark W. Geraci +14 more
TL;DR: The A/J mouse-urethane model reflects significant molecular details of human lung AC, and comparison of changes in orthologous gene expression may provide novel insights into lung carcinogenesis.
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Fibroblast Growth Factor (FGF) and FGF Receptor-Mediated Autocrine Signaling in Non-Small-Cell Lung Cancer Cells
Lindsay Marek,Kathryn E. Ware,Alexa Fritzsche,Paula Hercule,Wallace R. Helton,Jennifer E. Smith,Lee Apostle Mcdermott,Christopher D. Coldren,Raphael A. Nemenoff,Daniel T. Merrick,Barbara Helfrich,Paul A. Bunn,Lynn E. Heasley +12 more
TL;DR: FGF2, FGF9 and their respective high-affinity FGFRs comprise a growth factor autocrine loop that is active in a subset of gefitinib-insensitive NSCLC cell lines.