C
Cleverson Busso
Researcher at Federal University of Technology - Paraná
Publications - 33
Citations - 601
Cleverson Busso is an academic researcher from Federal University of Technology - Paraná. The author has contributed to research in topics: Coenzyme Q – cytochrome c reductase & Chemistry. The author has an hindex of 9, co-authored 30 publications receiving 497 citations. Previous affiliations of Cleverson Busso include University of São Paulo & Universidade Estadual de Maringá.
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Journal ArticleDOI
ADCK3, an Ancestral Kinase, Is Mutated in a Form of Recessive Ataxia Associated with Coenzyme Q10 Deficiency
Clotilde Lagier-Tourenne,Meriem Tazir,Luis C. López,Catarina M. Quinzii,Mirna Assoum,Nathalie Drouot,Cleverson Busso,Samira Makri,Lamia Alipacha,Traki Benhassine,Mathieu Anheim,David A. Lynch,Christelle Thibault,Frédéric Plewniak,Laurent Bianchetti,Christine Tranchant,Olivier Poch,Salvatore DiMauro,Jean-Louis Mandel,Mario H. Barros,Michio Hirano,M. Koenig +21 more
TL;DR: A SNP-based genome-wide scan in a large consanguineous family revealed a locus for autosomal-recessive ataxia at chromosome 1q41, and a phylogenetic analysis shows that ADCK3 belongs to the family of atypical kinases, which includes phosphoinositide and choline kinase, suggesting that ADCk3 plays an indirect regulatory role in ubiquinone biosynthesis possibly as part of a feedback loop that regulates ATP production.
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Influence of time, temperature and solvent on the extraction of bioactive compounds of Baccharis dracunculifolia: In vitro antioxidant activity, antimicrobial potential, and phenolic compound quantification
Maira Casagrande,Juliano Zanela,Américo Wagner Júnior,Cleverson Busso,Jéssica Wouk,Genice Iurckevicz,Paula Fernandes Montanher,Fabio Yamashita,Carlos Ricardo Maneck Malfatti +8 more
TL;DR: In this paper, the best conditions for the extraction of phenolic compounds with antioxidant activity (AA) of the Baccharis dracunculifolia DC (Bd) plant using response surface methodology (RSM) were investigated.
Journal ArticleDOI
Over-expression of COQ10 in Saccharomyces cerevisiae inhibits mitochondrial respiration.
Mariana A. Zampol,Cleverson Busso,Fernando Gomes,Jose Ribamar Ferreira-Junior,Alexander Tzagoloff,Mario H. Barros +5 more
TL;DR: When over-produced in coq mutants, Coq8p counteracts turnover of Coq3p and Coq4p subunits of the Q-biosynthetic complex, which can account for the observed rescue by COQ8 of the respiratory defect in strains over-producing Coq10p.
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Chemical composition, antifungal and antioxidant activity of essential oils from Baccharis dracunculifolia and Pogostemon cablin against Fusarium graminearum.
TL;DR: Essential oil from P. cablin has greater anti-phytopathogenic and antioxidant activity than that from B. dracunculifolia, and had antioxidant activity in free radical sequestration experiments, where as oil from B.'s place had limited effects.
Journal ArticleDOI
Saccharomyces cerevisiae coq10 null mutants are responsive to antimycin A
Cleverson Busso,Erich B. Tahara,Renata Ogusucu,Ohara Augusto,Jose Ribamar Ferreira-Junior,Alexander Tzagoloff,Alicia J. Kowaltowski,Mario H. Barros +7 more
TL;DR: The results show that coq10 mutants respond to antimycin A, indicating an active Q‐cycle in these mutants, even though they are unable to transport electrons through cytochrome c and are not responsive to myxothiazol.