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Mario H. Barros

Researcher at University of São Paulo

Publications -  57
Citations -  3912

Mario H. Barros is an academic researcher from University of São Paulo. The author has contributed to research in topics: Saccharomyces cerevisiae & Mitochondrion. The author has an hindex of 24, co-authored 54 publications receiving 3647 citations. Previous affiliations of Mario H. Barros include Sao Paulo State University & Columbia University.

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The genome sequence of the plant pathogen Xylella fastidiosa

Andrew J. G. Simpson, +117 more
- 13 Jul 2000 - 
TL;DR: The complete genome sequence of X. fastidiosa clone 9a5c is reported, providing direct evidence of phage-mediated horizontal gene transfer and indicating that the molecular basis for bacterial pathogenicity is both conserved and independent of host.
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Mitochondria as a Source of Reactive Oxygen and Nitrogen Species: From Molecular Mechanisms to Human Health

TL;DR: The interaction between mitochondrial reactive oxygen and nitrogen species, and the involvement of these oxidants in mitochondrial diseases, cancer, neurological, and cardiovascular disorders are discussed.
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Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae.

TL;DR: In this paper, the effects of calorie restriction on mitochondrial respiration, reactive oxygen species release, and replicative and chronological life span were investigated in Saccharomyces cerevisiae.
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ADCK3, an Ancestral Kinase, Is Mutated in a Form of Recessive Ataxia Associated with Coenzyme Q10 Deficiency

TL;DR: A SNP-based genome-wide scan in a large consanguineous family revealed a locus for autosomal-recessive ataxia at chromosome 1q41, and a phylogenetic analysis shows that ADCK3 belongs to the family of atypical kinases, which includes phosphoinositide and choline kinase, suggesting that ADCk3 plays an indirect regulatory role in ubiquinone biosynthesis possibly as part of a feedback loop that regulates ATP production.
Journal Article

Higher respiratory activity decreases mitochondrial reactive oxygen release and increases lifespan in Saccharomyces cerevisiae

TL;DR: The results suggest that yeast aging is linked to changes in mitochondrial metabolism and oxidative stress and that mild mitochondrial uncoupling can increase both chronological and replicative life span.