Mathieu Anheim

TL;DR: Neurologic Features in SARS-CoV-2 Infection In a consecutive series of 64 patients with Covid-19 and ARDS, 58 of whom underwent neurologic examination, severe agitation and corticospinal signs were found.

TL;DR: A SNP-based genome-wide scan in a large consanguineous family revealed a locus for autosomal-recessive ataxia at chromosome 1q41, and a phylogenetic analysis shows that ADCK3 belongs to the family of atypical kinases, which includes phosphoinositide and choline kinase, suggesting that ADCk3 plays an indirect regulatory role in ubiquinone biosynthesis possibly as part of a feedback loop that regulates ATP production.

TL;DR: TheDelirium/neurological symptoms in COVID-19 patients were responsible for longer mechanical ventilation compared to the patients without delirium or abnormal neurological symptoms, and could be secondary to systemic inflammatory reaction to SARS-CoV-2.

TL;DR: In this article, a series of 67 previously reported and 58 novel ataxic patients who underwent senataxin gene sequencing because of suspected ataxia with oculomotor apraxia type 2 (AOA2) was compiled.

TL;DR: It is demonstrated that proline 47 is a key amino acid essential for maintaining the WWOX protein fully functional, with its mutation into a threonine resulting in a loss of peptide interaction for the first WW domain.