C
Clifford W. Shults
Researcher at University of California, San Diego
Publications - 73
Citations - 8885
Clifford W. Shults is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Substantia nigra & Dopaminergic. The author has an hindex of 43, co-authored 73 publications receiving 8378 citations. Previous affiliations of Clifford W. Shults include United States Department of Veterans Affairs & Veterans Health Administration.
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Journal ArticleDOI
Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline.
Clifford W. Shults,David Oakes,Karl Kieburtz,M. Flint Beal,Richard H. Haas,Sandy Plumb,Jorge L. Juncos,John G. Nutt,Ira Shoulson,Julie H. Carter,Katie Kompoliti,Joel S. Perlmutter,Stephen G. Reich,Matthew B. Stern,Ray L. Watts,Roger Kurlan,Eric Molho,Madaline B. Harrison,Mark F. Lew +18 more
TL;DR: Coenzyme Q10 appears to slow the progressive deterioration of function in PD, but these results need to be confirmed in a larger study.
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Neuropsychological evidence for multiple implicit memory systems: a comparison of Alzheimer's, Huntington's, and Parkinson's disease patients
TL;DR: The results for the PD patients suggest that the demented PD patients have endured damage to the neurologic systems subserving both motor learning and lexical priming.
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Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS).
Gregor K. Wenning,François Tison,Klaus Seppi,Cristina Sampaio,Anja Diem,Farid Yekhlef,Imad Ghorayeb,Fabienne Ory,Monique Galitzky,Tommaso Scaravilli,M Bozi,Carlo Colosimo,Sid Gilman,Clifford W. Shults,Niall Quinn,Olivier Rascol,Werner Poewe +16 more
TL;DR: The UMSARS appears to be a multidimensional, reliable, and valid scale for semiquantitative clinical assessments of MSA patients.
Journal ArticleDOI
Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters
Edward Rockenstein,Margaret Mallory,Makoto Hashimoto,David D. Song,David D. Song,Clifford W. Shults,Clifford W. Shults,Ingrid Lang,Eliezer Masliah +8 more
TL;DR: Comparisons of patterns of human α‐synuclein accumulation in the brains of transgenic mice expressing this molecule from the murine Thy‐1 and platelet‐derived growth factor (PDGF) promoters show a more widespread accumulation of this protein in transgenic mouse brains.
Journal ArticleDOI
The Adult Substantia Nigra Contains Progenitor Cells with Neurogenic Potential
D. Chichung Lie,Gustavo Dziewczapolski,Andrew R. Willhoite,Brian K. Kaspar,Clifford W. Shults,Fred H. Gage +5 more
TL;DR: It is suggested that progenitor cells reside in the adult SN and can give rise to new neurons when exposed to appropriate environmental signals, which might be useful for future endogenous cell replacement strategies in Parkinson's disease.