Coraline Radermecker

TL;DR: Neutrophil extracellular traps infiltrate the airway, interstitial, and vascular compartments, supporting the hypothesis that they may drive several aspects of COVID-19 lung pathology and represent therapeutic targets.

TL;DR: In a mouse model of allergic airway hypersensitivity, it is shown that rhinovirus infection triggers dsDNA release associated with the formation of neutrophil extracellular traps (NETs), known as NETosis, which contribute to the pathogenesis and may represent potential therapeutic targets of rhinOVirus-induced asthma exacerbations.

TL;DR: Using single-cell RNA-sequencing, two phenotypically distinct subpopulations of long-lived monocyte-derived IM are shown, i.e. CD206+ and CD206−IM, as well as a discrete population of extravasating CD64+CD16.2+ monocytes.

TL;DR: It is found that CpG exposure leads to higher numbers of lung interstitial macrophages that prevent allergic inflammation through the production of the regulatory cytokine interleukin‐10.

TL;DR: It is shown that lung neutrophils in mice exposed to three distinct pro-allergic conditions release neutrophil extracellular traps that potentiate allergen uptake by dendritic cells and type 2 allergic inflammation.