H
Heidi Makrinioti
Researcher at Imperial College Healthcare
Publications - 41
Citations - 1558
Heidi Makrinioti is an academic researcher from Imperial College Healthcare. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 13, co-authored 30 publications receiving 1174 citations. Previous affiliations of Heidi Makrinioti include Queen Mary University of London & National and Kapodistrian University of Athens.
Papers
More filters
Journal ArticleDOI
IL-33–Dependent Type 2 Inflammation during Rhinovirus-induced Asthma Exacerbations In Vivo
David A. Jackson,David A. Jackson,Heidi Makrinioti,Batika M. J. Rana,Betty Shamji,Maria-Belen Trujillo-Torralbo,Maria-Belen Trujillo-Torralbo,Joseph Footitt,Joseph Footitt,Jerico del-Rosario,Jerico del-Rosario,Aurica G. Telcian,A A Nikonova,Jie Zhu,Julia Aniscenko,Leila Gogsadze,Eteri Bakhsoliani,Stephanie Traub,Jaideep Dhariwal,Jaideep Dhariwal,James D. Porter,Duncan Hunt,Toby Hunt,Trevor Hunt,Luminita A. Stanciu,Musa Khaitov,Nathan W. Bartlett,Michael R. Edwards,Onn Min Kon,Patrick Mallia,Patrick Mallia,Nikolaos G. Papadopoulos,Cezmi A. Akdis,John Westwick,Matthew J. Edwards,David J. Cousins,Ross P. Walton,Sebastian L. Johnston,Sebastian L. Johnston +38 more
TL;DR: IL-33 and type 2 cytokines are induced during a rhinovirus-induced asthma exacerbation in vivo and relate to exacerbation severity, which is a novel therapeutic approach for asthma exacerbations.
Journal ArticleDOI
Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
Marie Toussaint,David A. Jackson,Dawid Swieboda,Anabel Guedán,Theodora-Dorita Tsourouktsoglou,Yee Man Ching,Coraline Radermecker,Heidi Makrinioti,Julia Aniscenko,Michael R. Edwards,Roberto Solari,Frédéric Farnir,Venizelos Papayannopoulos,Fabrice Bureau,Thomas Marichal,Sebastian L. Johnston +15 more
TL;DR: In a mouse model of allergic airway hypersensitivity, it is shown that rhinovirus infection triggers dsDNA release associated with the formation of neutrophil extracellular traps (NETs), known as NETosis, which contribute to the pathogenesis and may represent potential therapeutic targets of rhinOVirus-induced asthma exacerbations.
Journal ArticleDOI
Vitamin D modulation of innate immune responses to respiratory viral infections.
Mihnea Zdrenghea,Heidi Makrinioti,Cristina Bagacean,Andrew Bush,Sebastian L. Johnston,Luminita A. Stanciu,Luminita A. Stanciu +6 more
TL;DR: The in vitro data on the role of vitamin D in antiviral innate immunity, the data concerning the deficient levels ofitamin D in lung diseases, and the in vivo role of supplementation as protection against respiratory viral infections in healthy individuals and in patients with chronic respiratory diseases are reviewed.
Journal ArticleDOI
Research needs in allergy: an EAACI position paper, in collaboration with EFA
Nikolaos G. Papadopoulos,Ioana Agache,Sevim Bavbek,B. M. Bilo,Fulvio Braido,Victoria Cardona,Adnan Custovic,Jan Demonchy,Pascal Demoly,Philippe Eigenmann,Jacques Gayraud,Clive Grattan,Enrico Heffler,Peter Hellings,Marek Jutel,Edward F. Knol,Jan Lötvall,Antonella Muraro,Lars K. Poulsen,Graham Roberts,Peter Schmid-Grendelmeier,Chrysanthi Skevaki,Massimo Triggiani,Ronald Vanree,Thomas Werfel,Breda Flood,Susanna Palkonen,Roberta Savli,Pia Allegri,Isabella Annesi-Maesano,Francesco Annunziato,Darío Antolín-Amérigo,Christian Apfelbacher,Miguel Blanca,Ewa Bogacka,Patrizia Bonadonna,Matteo Bonini,Onur Boyman,Knut Brockow,Peter Burney,Jeroen Buters,Indre Butiene,Moises A. Calderon,Lars-Olaf Cardell,Jean-Christoph Roger J-P Caubet,Sevcan Celenk,Ewa Cichocka-Jarosz,Cemal Cingi,Mariana Couto,Nicolette W. deJong,Stefano Del Giacco,Nikolaos Douladiris,Filippo Fassio,Jean-Luc Fauquert,Javier Fernández,Montserrat Fernandez Rivas,Marta Ferrer,Carsten Flohr,James Gardner,Jon Genuneit,Philippe Gevaert,Anna Groblewska,Eckard Hamelmann,Hans Jürgen Hoffmann,Karin Hoffmann-Sommergruber,Lilit Hovhannisyan,Valérie Hox,Frode L. Jahnsen,Ömer Kalayci,Ayse Fusun Kalpaklioglu,Jörg Kleine-Tebbe,George N. Konstantinou,Marcin Kurowski,Susanne Lau,Roger Lauener,Antti Lauerma,Kirsty Logan,Antoine Magnan,Joanna Makowska,Heidi Makrinioti,Paraskevi Mangina,Felicia Manole,Adriano Mari,Angel Mazon,Clare Mills,Ervinç Mingomataj,Bodo Niggemann,Gunnar Nilsson,Markus Ollert,Liam O'Mahony,Serena O'Neil,Gianni Pala,Alberto Papi,Gianni Passalacqua,Michael R. Perkin,Oliver Pfaar,Constantinos Pitsios,Santiago Quirce,Ulrike Raap,Monika Raulf-Heimsoth,Claudio Rhyner,Paula Robson-Ansley,Rodrigo Rodrigues Alves,Zeljka Roje,Carmen Rondon,Odilija Rudzeviciene,Franziska Ruëff,Maia Rukhadze,Gabriele Rumi,Cansin Sackesen,Alexandra F. Santos,Alexandra F. Santos,Annalisa Santucci,Christian Scharf,Carsten B. Schmidt-Weber,B Schnyder,Jürgen Schwarze,Gianenrico Senna,Svetlana Sergejeva,Sven Seys,Andrea Siracusa,Isabel Skypala,Milena Sokolowska,François Spertini,Radoslaw Spiewak,Aline B. Sprikkelman,Gunter J. Sturm,Ines Swoboda,Ingrid Terreehorst,Elina Toskala,Claudia Traidl-Hoffmann,Carina Venter,Berber Vlieg-Boerstra,Paul Whitacker,Margitta Worm,Paraskevi Xepapadaki,Cezmi A. Akdis +136 more
TL;DR: The present EAACI Position Paper, in collaboration with EFA, highlights the most important research needs in the field of allergy to serve as key recommendations for future research funding at the national and European levels.
Journal ArticleDOI
Bronchiolitis needs a revisit: Distinguishing between virus entities and their treatments
Tuomas Jartti,Hermelijn H. Smits,Klaus Bønnelykke,Ozlem Bircan,Varpu Elenius,Jon R Konradsen,Jon R Konradsen,Paraskevi Maggina,Heidi Makrinioti,Jakob Stokholm,Gunilla Hedlin,Gunilla Hedlin,Nikolaos G. Papadopoulos,Nikolaos G. Papadopoulos,Marek Ruszczyński,Klaudia Ryczaj,Bianca Schaub,Jürgen Schwarze,Chrysanthi Skevaki,Katarina Stenberg-Hammar,Katarina Stenberg-Hammar,Wojciech Feleszko +21 more
TL;DR: The first episode of severe bronchiolitis in under 2‐year‐old children is a critical event and an important opportunity for designing secondary prevention strategies for asthma, using the viral etiology as the differentiating factor.