Cornelia Schönbauer

TL;DR: A role in muscle is identified for 2,785 genes, many of which are phylogenetically conserved, including genes implicated in mammalian sarcomere organization and human muscle diseases.

TL;DR: Ultramicroscopy reconstructions of the flight musculature, the nervous system, and the digestive tract of entire, chemically cleared, drosophila in autofluorescent light verify that the anatomy of a whole fly, including the filigree spatial organization of the direct flight muscles, can be analysed from a single ultramicroScopy reconstruction.

TL;DR: It is proposed that Spalt proteins switch myofibres from tubular to fibrillar fate during development, a function potentially conserved in the vertebrate heart—a stretch-activated muscle sharing features with insect flight muscle.

TL;DR: It is reported that a signaling active version of Ret (RetMEN2B) rescues muscle degeneration, disintegration of mitochondria and ATP content of Pink1 mutants, providing a novel mechanism underlying Ret‐mediated cell protection in a situation relevant for human PD.

TL;DR: It is shown that spalt major (salm) determines fibrillar muscle physiology by regulating transcription and alternative splicing of a large set of sarcomeric proteins, and the RNA‐binding protein Arrest (Aret) is identified as downstream of salm.