M
Martin Radolf
Researcher at Research Institute of Molecular Pathology
Publications - 10
Citations - 1319
Martin Radolf is an academic researcher from Research Institute of Molecular Pathology. The author has contributed to research in topics: Gene & Transcription factor. The author has an hindex of 8, co-authored 10 publications receiving 1212 citations.
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Journal ArticleDOI
The profile of repeat‐associated histone lysine methylation states in the mouse epigenome
Joost H.A. Martens,Roderick J. O'Sullivan,Ulrich Braunschweig,Susanne Opravil,Martin Radolf,Peter Steinlein,Thomas Jenuwein +6 more
TL;DR: A profile of repressive histone lysine methylation states for the repetitive complement of four distinct mouse epigenomes is defined and tandem repeats and dsRNA are suggested as primary triggers for more stable chromatin imprints.
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Systematic genetic analysis of muscle morphogenesis and function in Drosophila
Frank Schnorrer,Cornelia Schönbauer,Christoph C. H. Langer,Georg Dietzl,Maria Novatchkova,Katharina Schernhuber,Michaela Fellner,Anna Azaryan,Martin Radolf,Alexander Stark,Krystyna Keleman,Barry J. Dickson +11 more
TL;DR: A role in muscle is identified for 2,785 genes, many of which are phylogenetically conserved, including genes implicated in mammalian sarcomere organization and human muscle diseases.
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Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.
Kakkad Regha,Mathew A. Sloane,Ru Huang,Florian M. Pauler,Katarzyna E. Warczok,Balázs Melikant,Martin Radolf,Joost H.A. Martens,Gunnar Schotta,Thomas Jenuwein,Denise P. Barlow +10 more
TL;DR: M mammalian chromosome arms contain active chromatin interspersed with repressive chromatin resembling the type of heterochromatin previously considered a feature of centromeres, telomeres, and the inactive X chromosome.
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Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects
Cornelia Schönbauer,Jutta Distler,Nina Jährling,Nina Jährling,Martin Radolf,Hans-Ulrich Dodt,Hans-Ulrich Dodt,Manfred Frasch,Frank Schnorrer +8 more
TL;DR: It is proposed that Spalt proteins switch myofibres from tubular to fibrillar fate during development, a function potentially conserved in the vertebrate heart—a stretch-activated muscle sharing features with insect flight muscle.
Journal ArticleDOI
Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation.
Latifa Bakiri,Yasunari Takada,Martin Radolf,Robert Eferl,Moshe Yaniv,Erwin F. Wagner,Koichi Matsuo,Koichi Matsuo +7 more
TL;DR: Data show that a single Jun/c-Fos dimer is sufficient for osteoclast differentiation, likely due to its transactivation ability for a broader range of promoters, in particular consensus AP-1 sites.