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Cristina Ivan

Researcher at University of Texas MD Anderson Cancer Center

Publications -  197
Citations -  12070

Cristina Ivan is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 51, co-authored 182 publications receiving 9540 citations. Previous affiliations of Cristina Ivan include University of Texas Health Science Center at Houston & Leibniz University of Hanover.

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Journal Article

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER. : Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.

TL;DR: In this article, the authors identify tumour hypoxia as a regulator of DICER expression in large cohorts of breast cancer patients and show that reduced expression of the enzyme leads to derepression of the miR200 target ZEB1, stimulates the epithelial to mesenchymal transition and ultimately results in the acquisition of stem cell phenotypes in human mammary epithelial cells.
Proceedings ArticleDOI

Abstract 2871: Allele-specific modulation of cancer metabolism by a long noncoding RNA

TL;DR: This study shows that the long non-codingRNA CCAT2, located at 8q24 amplicon on cancer risk associated rs6983267 SNP, regulates cancer metabolism in vitro and in vivo, in an allele-specific manner by binding the cleavage factor I (CFIm) complex with distinct affinities, complementary to the risk for colon cancer.
Journal ArticleDOI

lncRNAs UC.145 and PRKG1-AS1 Determine the Functional Output of DKK1 in Regulating the Wnt Signaling Pathway in Gastric Cancer

TL;DR: Insight is provided into Wnt signaling in gastric cancer and support UC.145 as a potential novel predictive biomarker for the disease.