C
Cristina Ivan
Researcher at University of Texas MD Anderson Cancer Center
Publications - 197
Citations - 12070
Cristina Ivan is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 51, co-authored 182 publications receiving 9540 citations. Previous affiliations of Cristina Ivan include University of Texas Health Science Center at Houston & Leibniz University of Hanover.
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Journal ArticleDOI
targetHub: a programmable interface for miRNA–gene interactions
TL;DR: TargetHub as discussed by the authors is a CouchDB database of miRNA-gene interactions with an assortment of gene and miRNA identifiers, which can be used to integrate miRNA target interaction data directly into high-throughput bioinformatics analyses.
Journal ArticleDOI
Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.
Xue Wu,Cristina Mariana Niculite,Mihai Bogdan Preda,Annalisa Rossi,Toma Tebaldi,Toma Tebaldi,Elena Butoi,Mattie K. White,Oana Tudoran,Daniela N. Petrusca,Amber Jannasch,William P. Bone,Xingyue Zong,Fang Fang,Alexandrina Burlacu,Michelle T. Paulsen,Bradley A. Hancock,George E. Sandusky,Sumegha Mitra,Sumegha Mitra,Melissa L. Fishel,Melissa L. Fishel,Aaron Buechlein,Cristina Ivan,Spyros Oikonomopoulos,Myriam Gorospe,Amber L. Mosley,Milan Radovich,Milan Radovich,Utpal P. Davé,Utpal P. Davé,Jiannis Ragoussis,Kenneth P. Nephew,Kenneth P. Nephew,Bernard Mari,Alan McIntyre,Heiko Konig,Heiko Konig,Mats Ljungman,Mats Ljungman,Diana L. Cousminer,Paolo Macchi,Mircea Ivan,Mircea Ivan +43 more
TL;DR: The initial portrait of lincNORS is provided, a spliced lincRNA generated by the MIR193BHG locus, entirely distinct from the previously described miR-193b-365a tandem, which fine-tunes cellular sterol/steroid biosynthesis by repressing the expression of multiple pathway components.
Journal ArticleDOI
Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy
Lingegowda S. Mangala,Hongyu Wang,Dahai Jiang,Sherry Y. Wu,Anoma Somasunderam,David E. Volk,Ganesh L.R. Lokesh,Xin Li,Sunila Pradeep,Xianbin Yang,Monika Haemmerle,Cristian Rodriguez-Aguayo,Archana S. Nagaraja,Rajesha Rupaimoole,Emine Bayraktar,Recep Bayraktar,Li Li,Takemi Tanaka,Wei Hu,Cristina Ivan,Kshipra M. Gharpure,Michael McGuire,Varatharasa Thiviyanathan,Xinna Zhang,Sourindra Maiti,Nataliya Bulayeva,Hyun Jin Choi,Piotr L. Dorniak,Laurence J.N. Cooper,Kevin P. Rosenblatt,Gabriel Lopez-Berestein,David G. Gorenstein,Anil K. Sood +32 more
TL;DR: A better approach to target cancer-associated endothelial cells (ECs), reverse permeability and leakiness of tumor blood vessels, and improve delivery of chemotherapeutic agents to the tumor is reported.
Journal ArticleDOI
The hidden role of paxillin: localization to nucleus promotes tumor angiogenesis.
Kyunghee Noh,Duc-Hiep Bach,Hyun Jin Choi,Hyun Jin Choi,Mark Seungwook Kim,Sherry Y. Wu,Sunila Pradeep,Cristina Ivan,Min Soon Cho,Emine Bayraktar,Cristian Rodriguez-Aguayo,Santosh K. Dasari,Elaine Stur,Lingegowda S. Mangala,Gabriel Lopez-Berestein,Anil K. Sood +15 more
TL;DR: A previously unrecognized mechanism whereby nuclear PXN enhances angiogenesis by transcriptionally regulating SRC expression is demonstrated, which provides a new understanding of the role of PxN in regulating tumorAngiogenesis and growth.
Journal ArticleDOI
The non-coding RNome after splenectomy.
Mihnea P. Dragomir,Mihnea P. Dragomir,Stefan Tudor,Keishi Okubo,Masayoshi Shimizu,Meng Chen,Dana Elena Giza,William Ruixian He,Cristina Ivan,George A. Calin,Catalin Vasilescu +10 more
TL;DR: It is suggested that the ncRNAs potentially regulate the immune changes observed after splenectomy, as deregulated miRNAs control pathways involved in immunity, cancer and endothelial growth.