C
Cynthia J. Meininger
Researcher at Texas A&M University
Publications - 123
Citations - 11763
Cynthia J. Meininger is an academic researcher from Texas A&M University. The author has contributed to research in topics: Arginine & Nitric oxide. The author has an hindex of 53, co-authored 122 publications receiving 10819 citations. Previous affiliations of Cynthia J. Meininger include Oklahoma State University–Stillwater & Veterans Health Administration.
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Maternal Nutrition and Fetal Development
TL;DR: There is growing evidence that maternal nutritional status can alter the epigenetic state (stable alterations of gene expression through DNA methylation and histone modifications) of the fetal genome, which may provide a molecular mechanism for the impact of maternal nutrition on both fetal programming and genomic imprinting.
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VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells
TL;DR: It is concluded that VEGF upregulates ecNOS enzyme and elicits a biphasic stimulation of endothelial NO production, and regulates endothelial production of NO.
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Regulatory role for the arginine–nitric oxide pathway in metabolism of energy substrates
Wenjuan S. Jobgen,Susan K. Fried,Wenjiang J. Fu,Cynthia J. Meininger,Guoyao Wu,Guoyao Wu,Guoyao Wu +6 more
TL;DR: Modulation of the arginine-NO pathway through dietary supplementation with L-arginine or L-citrulline may aid in the prevention and treatment of the metabolic syndrome in obese humans and companion animals, and in reducing unfavorable fat mass in animals of agricultural importance.
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Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells
Hui Li,Cynthia J. Meininger,James R. Hawker,Tony E. Haynes,Diane Kepka-Lenhart,Sanjay K. Mistry,Sidney M. Morris,Guoyao Wu +7 more
TL;DR: The results indicate that arginase expression can modulate NO synthesis in bovine venular EC and that basal levels of arginases I and II are limiting for endothelial syntheses of polyamines, proline, and glutamate and may have important implications for wound healing, angiogenesis, and cardiovascular function.
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Beneficial effects of l-arginine on reducing obesity: potential mechanisms and important implications for human health
Jason R. McKnight,M. Carey Satterfield,Wenjuan S. Jobgen,Stephen B. Smith,Thomas E. Spencer,Cynthia J. Meininger,Catherine J. McNeal,Guoyao Wu,Guoyao Wu +8 more
TL;DR: Recent studies indicate that l-arginine supplementation stimulates mitochondrial biogenesis and brown adipose tissue development possibly through the enhanced synthesis of cell-signaling molecules as well as the increased expression of genes that promote whole-body oxidation of energy substrates.