M
Marc Stegger
Researcher at Statens Serum Institut
Publications - 199
Citations - 9101
Marc Stegger is an academic researcher from Statens Serum Institut. The author has contributed to research in topics: Medicine & Methicillin-resistant Staphylococcus aureus. The author has an hindex of 45, co-authored 159 publications receiving 6715 citations. Previous affiliations of Marc Stegger include Translational Genomics Research Institute & Murdoch University.
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Journal ArticleDOI
Staphylococcus aureus CC398: Host Adaptation and Emergence of Methicillin Resistance in Livestock
Lance B. Price,Marc Stegger,Henrik Hasman,Maliha Aziz,Jesper Larsen,Paal Skytt Andersen,Talima Pearson,Andrew E. Waters,Jeffrey T. Foster,James M. Schupp,John D. Gillece,Elizabeth M. Driebe,Cindy M. Liu,Cindy M. Liu,Burkhard Springer,Irena Zdovc,Antonio Battisti,Alessia Franco,Jacek Żmudzki,Stefan Schwarz,Patrick Butaye,Eric Jouy,Constança Pomba,M. Concepción Porrero,Raymond Ruimy,Tara C. Smith,D. Ashley Robinson,J. Scott Weese,Carmen Sofia Arriola,Fangyou Yu,Frédéric Laurent,Paul Keim,Paul Keim,Robert Skov,Frank Møller Aarestrup +34 more
TL;DR: The results strongly suggest that livestock-associated MRSA CC398 originated in humans as MSSA, which appears to have undergone a rapid radiation in conjunction with the jump from humans to livestock, where it subsequently acquired tetracycline and methicillin resistance.
Journal ArticleDOI
The Epidemic of Extended-Spectrum-β-Lactamase-Producing Escherichia coli ST131 Is Driven by a Single Highly Pathogenic Subclone, H30-Rx
Lance B. Price,Lance B. Price,James R. Johnson,Maliha Aziz,Maliha Aziz,Connie Clabots,Brian D. Johnston,Veronika Tchesnokova,Lora Nordstrom,Maria Billig,Sujay Chattopadhyay,Marc Stegger,Marc Stegger,Paal Skytt Andersen,Paal Skytt Andersen,Talima Pearson,Kim Riddell,Peggy Rogers,Delia Scholes,Barbara C. Kahl,Paul Keim,Paul Keim,Evgeni V. Sokurenko +22 more
TL;DR: P pulsed-field gel electrophoresis and whole-genome sequencing are applied to reconstruct the evolutionary history of the ST131 clone and suggest that the high prevalence of CTX-M-15 production among ST131 isolates is due primarily to the expansion of a single, highly virulent subclone, H30-Rx.
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Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015
Henrik Hasman,Anette M. Hammerum,Frank Hansen,Rene S. Hendriksen,Bente Olesen,Yvonne Agersø,Ea Zankari,Pimlapas Leekitcharoenphon,Marc Stegger,Rolf Sommer Kaas,Lina Cavaco,Dennis S. Hansen,Frank Møller Aarestrup,Robert Skov +13 more
TL;DR: The plasmid-mediated colistin resistance gene, mcr-1, was detected in an Escherichia coli isolate from a Danish patient with bloodstream infection and in five E. coli isolates from imported chicken meat.
Journal ArticleDOI
Rapid detection, differentiation and typing of methicillin-resistant Staphylococcus aureus harbouring either mecA or the new mecA homologue mecALGA251
Marc Stegger,Paal Skytt Andersen,Angela M. Kearns,Bruno Pichon,Mark A. Holmes,Giles Edwards,Frédéric Laurent,Christopher Teale,Robert Skov,Anders Rhod Larsen +9 more
TL;DR: Over a 2-month period, 12 new MRSA cases caused by isolates carrying mecA(LGA251) were identified, emphasizing the clinical importance of testing for these new MR SA isolates.
Journal ArticleDOI
Mapping the Evolution of Hypervirulent Klebsiella pneumoniae
Carsten Struve,Chandler C. Roe,Marc Stegger,Steen Gustav Stahlhut,Dennis S. Hansen,David M. Engelthaler,Paal Skytt Andersen,Elizabeth M. Driebe,Paul Keim,Karen A. Krogfelt +9 more
TL;DR: The phylogenetic background of hvKP isolates is revealed, revealing that CC23 is a unique clonal lineage, clearly distinct from nonhypervirulent strains, and novel genetic determinants uniquely associated with CC23 were identified.