Dae Hyun Kim

TL;DR: 3D bioprinted artificial trachea were effective in respiratory epithelium regeneration and neo-cartilage formation was observed only in a localized area and d-MSC showed a relatively higher level of glycosaminoglycan accumulation and chondrogenic marker gene expression than MSC in vitro.

TL;DR: The artificial trachea created via a tissue engineering method using 3D bio-printing was effective in the regeneration of respiratory epithelium, but not in cartilage regeneration.

TL;DR: Improved patency in a porcine vessel for 18 d is demonstrated while occlusive vascular remodeling occurs, and insights will help advance vascular graft design.

TL;DR: Ex vivo and in vivo animal studies demonstrate enhanced drug delivery efficiency, efficacy for IH reduction, and safety of MN mesh, and wrappable MN meshes effectively suppressed side effects such as IH due to mechanical constriction, loss of toxic drug to the surroundings, and cell death that were frequently observed with other previous perivascular drug delivery devices.

TL;DR: A microchannel-patterned gelatin hydrogel that is able to rescue mouse and porcine models of hindlimb ischemia and reveal hypoxia and neighboring vessels as major causative factors of the beneficial function is presented.