D
Damian L. Trujillo
Researcher at Stanford University
Publications - 2
Citations - 144
Damian L. Trujillo is an academic researcher from Stanford University. The author has contributed to research in topics: CCL5 & Malaria. The author has an hindex of 2, co-authored 2 publications receiving 104 citations.
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Journal ArticleDOI
A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence
Murad R. Mamedov,Anja Scholzen,Ramesh V. Nair,Katherine Cumnock,Justin A. Kenkel,Jose Henrique M. Oliveira,Jose Henrique M. Oliveira,Damian L. Trujillo,Naresha Saligrama,Yue Zhang,Florian Rubelt,David Schneider,Yueh-hsiu Chien,Robert W. Sauerwein,Mark M. Davis,Mark M. Davis +15 more
TL;DR: Findings point to an M‐CSF‐producing T cell subset that fulfills a specialized protective role in the later stage of malaria infection when T cells have declined, and exhibits a distinct transcriptional profile that includes abundantly expressed M‐ CSF, which protects against Plasmodium recurrence.
Journal ArticleDOI
Renal control of disease tolerance to malaria.
Susana Ramos,Ana Rita Carlos,Balamurugan Sundaram,Viktória Jeney,Ana Ribeiro,Raffaella Gozzelino,Claudia Bank,Erida Gjini,Faouzi Braza,Rui Martins,Temitope W. Ademolue,Birte Blankenhaus,Zélia Gouveia,Pedro Faísca,Damian L. Trujillo,Silvia Cardoso,Sofia Rebelo,Laura del Barrio,Abolfazl Zarjou,Subhashini Bolisetty,Anupam Agarwal,Anupam Agarwal,Miguel P. Soares +22 more
TL;DR: It is demonstrated that the establishment of disease tolerance to malaria relies on a tissue damage-control mechanism that operates specifically in renal proximal tubule epithelial cells (RPTEC), which relies on the induction of heme oxygenase-1 and ferritin H chain via a mechanism that involves the transcription-factor nuclear-factor E2-related factor-2 (NRF2).