Danfeng Sun

TL;DR: It is found that Fusobacterium (F.) nucleatum was abundant in colorectal cancer tissues in patients with recurrence post chemotherapy, and was associated with patient clinicopathological characterisitcs, and bioinformatic and functional studies demonstrated that F. nucleatum promoted coloreCTal cancer resistance to chemotherapy.

TL;DR: It is revealed that GClnc1 is an oncogenic lncRNA in human gastric cancer, which was upregulated and associated with tumorigenesis, tumor size, metastasis, and poor prognosis in Gastric cancer.

TL;DR: Clinically, both high expression of BFAL1 and high abundance of ETBF in CRC tissues predicted poor outcomes for patients with CRC, suggesting BFAL 1 is a mediator of ET BF-induced carcinogenesis and may be a potential therapeutic target for ETBF-induced CRC.

TL;DR: In this article, the authors show that deletion of SIRT5 causes a marked decrease in 13C-glutamine incorporation into tricarboxylic acid (TCA) cycle intermediates and glutamine-derived non-essential amino acids.

TL;DR: Fecal C. symbiosum is a promising biomarker for early and noninvasive detection of colorectal cancer, being more effective than F. nucleatum, FIT and CEA, and combined with Fusobacterium nucleatum and FIT may improve the diagnosis power.