Ta Chung Yu

TL;DR: It is found that Fusobacterium (F.) nucleatum was abundant in colorectal cancer tissues in patients with recurrence post chemotherapy, and was associated with patient clinicopathological characterisitcs, and bioinformatic and functional studies demonstrated that F. nucleatum promoted coloreCTal cancer resistance to chemotherapy.

TL;DR: It is revealed that GClnc1 is an oncogenic lncRNA in human gastric cancer, which was upregulated and associated with tumorigenesis, tumor size, metastasis, and poor prognosis in Gastric cancer.

TL;DR: In this article , the role of metformin in Fusobacterium (F.) nucleatum-infected colorectal cancer cells was confirmed using cell counting kit 8 assays and CRC xenograft mice.

TL;DR: In this article , the authors demonstrate that host's urea cycle metabolism is significantly activated during colorectal tumorigenesis, accompanied by the absence of beneficial bacteria with ureolytic capacity, such as Bifidobacterium.

TL;DR: This paper showed that metformin treatment expanded the proportion of CD8+ T cells and potentiated their function in colorectal cancer (CRC) using single-cell RNA sequencing.