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Ya-Nan Yu

Researcher at Shanghai Jiao Tong University

Publications -  11
Citations -  1504

Ya-Nan Yu is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Cell growth & Cancer. The author has an hindex of 9, co-authored 11 publications receiving 949 citations. Previous affiliations of Ya-Nan Yu include Qingdao University.

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Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy.

TL;DR: It is found that Fusobacterium (F.) nucleatum was abundant in colorectal cancer tissues in patients with recurrence post chemotherapy, and was associated with patient clinicopathological characterisitcs, and bioinformatic and functional studies demonstrated that F. nucleatum promoted coloreCTal cancer resistance to chemotherapy.
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Berberine may rescue Fusobacterium nucleatum -induced colorectal tumorigenesis by modulating the tumor microenvironment

TL;DR: F.ucleatum colonization in the intestine may prompt colorectal tumorigenesis, and BBR could rescue F. nucleatum-induced coloreCTal tumorsigenesis by modulating the tumor microenvironment and blocking the activation of tumorigenisation-related pathways.
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Probiotics Clostridium butyricum and Bacillus subtilis ameliorate intestinal tumorigenesis

TL;DR: This work establishes a basis for the protective role of probiotics B. subtilis and C. butyricum in intestinal tumorigenesis and inhibits the development of DMH-induced CRC.
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Knockdown of ZFX inhibits gastric cancer cell growth in vitro and in vivo via downregulating the ERK-MAPK pathway.

TL;DR: It is demonstrated for the first time that knockdown of ZFX inhibited gastric cancer cell growth in vitro and in vivo via downregulating the extracellular signal-regulated kinase/mitogen-activated protein kinase (ERK-MAPK) pathway.