Daniel Lockshon

TL;DR: Examination of large-scale yeast two-hybrid screens reveals interactions that place functionally unclassified proteins in a biological context, interactions between proteins involved in the same biological function, and interactions that link biological functions together into larger cellular processes.

TL;DR: It is proposed that replication forks are arrested in a directional manner through the binding of one or more proteins to two closely spaced sites in the RFB.

TL;DR: It is shown here that resolvase deficiency causes a larger proportion of molecules to be linked together by recombination junctions, resulting in the aggregation of mtDNA into a small number of cytological structures, which can account for the increased mitotic loss of mt DNA and the altered pattern of mitochondrial segregation from zygotes.

TL;DR: Cloning by genetic recombination obviates the need for ligations or bacterial manipulations and should permit convenient global approaches to gene function that require the assay of each putative yeast gene.

TL;DR: It is proposed that yeast deficient in peroxisomal and other functions are sensitive to oleate perhaps because of an inability to effectively control the fatty acid composition of membrane phospholipids.