D
Daniel M. Brown
Researcher at Laboratory of Molecular Biology
Publications - 153
Citations - 3870
Daniel M. Brown is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Nucleoside & Hydroxylamine. The author has an hindex of 34, co-authored 149 publications receiving 3805 citations. Previous affiliations of Daniel M. Brown include Kettering University & Worcester Foundation for Biomedical Research.
Papers
More filters
Journal ArticleDOI
Effect of nitrogen and of catalase on hydroxylamine and hydrazine mutagenesis.
Journal ArticleDOI
Nucleotides. Part XXVII. The structures of adenylic acids a and b
Journal ArticleDOI
A thymine-like base analogue forms wobble pairs with adenine in a Z-DNA duplex.
Geertrui S. Schuerman,Luc Van Meervelt,David Loakes,Daniel M. Brown,Paul Kong Thoo Lin,Madeleine H. Moore,Stephen A. Salisbury +6 more
TL;DR: In this article, it was shown that P·A base-pairs are of the wobble type, which is inconsistent with other evidence from hybridization and NMR studies of P-containing oligonucleotides, which suggests that, while P can form stable basepairs with either A or G, thyminelike properties are more pronounced.
Journal ArticleDOI
Synthesis and enzymatic incorporation of a novel, bicyclic pyrimidine nucleoside: a thymidine mimic
David Loakes,Daniel M. Brown,Stephen A. Salisbury,Mark Mcdougall,Constantin Neagu,Satyam Nampalli,Shiv Kumar +6 more
TL;DR: In this article, a ring-opening and rearrangement reaction of a furanopyrimidine nucleoside with anhydrous hydrazine provided a novel 6,6-bicyclic pyrimidopyridazin-7-one (dH, 4 ), whose structure was confirmed by X-ray crystallography.
Journal ArticleDOI
Use of 5-nitroindole-2'-deoxyribose-5'-triphosphate for labelling and detection of oligonucleotides.
C. L. Smith,A. C. Simmonds,A. L. Hamilton,D. L. Martin,A. G. Lashford,David Loakes,F. Hill,Daniel M. Brown +7 more
TL;DR: The 5'-triphosphate of 5-nitroindole-2'-deoxyriboside has been shown to be a good substrate for terminal deoxynucleotidyl transferase (TdT) and a new method for the detection of nucleic acid probes is prepared.