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Daniela Digles
Researcher at University of Vienna
Publications - 22
Citations - 1300
Daniela Digles is an academic researcher from University of Vienna. The author has contributed to research in topics: WikiPathways : Pathways for the people & Transporter Classification Database. The author has an hindex of 10, co-authored 22 publications receiving 745 citations.
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Journal ArticleDOI
WikiPathways : a multifaceted pathway database bridging metabolomics to other omics research
Denise Slenter,Martina Kutmon,Kristina Hanspers,Anders Riutta,Jacob Windsor,Nuno Nunes,Jonathan Mélius,Elisa Cirillo,Susan L. Coort,Daniela Digles,Friederike Ehrhart,Pieter Giesbertz,Marianthi Kalafati,Marvin Martens,Ryan A. Miller,Kozo Nishida,Linda Rieswijk,Andra Waagmeester,Lars M. T. Eijssen,Lars M. T. Eijssen,Chris T. Evelo,Alexander R. Pico,Egon Willighagen +22 more
TL;DR: There is a doubling of the number of annotated metabolite nodes in WikiPathways and an OpenAPI documentation of the authors' web services and the FAIR annotation of resources to increase the interoperability of the knowledge encoded in these pathways and experimental omics data.
Journal ArticleDOI
WikiPathways: connecting communities.
Marvin Martens,Ammar Ammar,Anders Riutta,Andra Waagmeester,Denise Slenter,Kristina Hanspers,Ryan A. Miller,Daniela Digles,Elisson Nogueira Lopes,Friederike Ehrhart,Lauren J. Dupuis,Laurent A. Winckers,Susan L. Coort,Egon Willighagen,Chris T. Evelo,Alexander R. Pico,Martina Kutmon +16 more
TL;DR: The growth of WikiPathways over the last three years is shown, the new communities and collaborations of pathway authors and curators are highlighted, and various technologies to connect to external resources and initiatives are described.
Journal ArticleDOI
The RESOLUTE consortium: unlocking SLC transporters for drug discovery.
Giulio Superti-Furga,Daniel Lackner,Tabea Wiedmer,Alvaro Ingles-Prieto,Barbara Barbosa,Enrico Girardi,Ulrich Goldmann,Bettina Gürtl,Kristaps Klavins,Christoph Klimek,Sabrina Lindinger,Eva Liñeiro-Retes,André C. Müller,Svenja Onstein,Gregor Redinger,Daniela Reil,Vitaly Sedlyarov,Gernot Wolf,Matthew Crawford,Robert Everley,David Hepworth,Shenping Liu,Stephen Noell,Mary Piotrowski,Robert V. Stanton,Hui Zhang,Salvatore Corallino,Andrea Faedo,Maria Insidioso,Giovanna Maresca,Loredana Redaelli,Francesca Sassone,Lia Scarabottolo,Michela Stucchi,Paola Tarroni,Sara Tremolada,Helena Batoulis,Andreas Becker,Eckhard Bender,Yung-Ning Chang,Alexander Ehrmann,Anke Müller-Fahrnow,Vera Pütter,Diana Zindel,Bradford Hamilton,Martin Lenter,Diana Santacruz,Coralie Viollet,Charles E. Whitehurst,Kai Johnsson,Philipp Leippe,Birgit Baumgarten,Lena Chang,Yvonne Ibig,Martin Pfeifer,Jürgen Reinhardt,Julian Schönbett,Paul Selzer,Klaus Seuwen,Charles Bettembourg,Bruno Biton,Jörg Czech,Hélène de Foucauld,Michel Didier,Thomas Licher,Vincent Mikol,Antje Pommereau,Frédéric Puech,Veeranagouda Yaligara,Aled M. Edwards,Brandon J. Bongers,Laura H. Heitman,Ad P. IJzerman,Huub J. Sijben,Gerard J. P. van Westen,Justine Grixti,Douglas B. Kell,Farah Mughal,Neil Swainston,Marina Wright-Muelas,Tina Bohstedt,N.A. Burgess-Brown,Liz Carpenter,Katharina L. Dürr,Jesper Hansen,Andreea Scacioc,Giulia Banci,Claire Colas,Daniela Digles,Gerhard F. Ecker,Barbara Füzi,Viktoria Gamsjäger,Melanie Grandits,Riccardo Martini,Florentina Troger,Patrick Altermatt,Cédric Doucerain,Franz Dürrenberger,Vania Manolova,Anna-Lena Steck,Hanna Sundström,Maria Wilhelm,Claire M. Steppan +102 more
TL;DR: The Innovative Medicines Initiative Consortium RESOLUTE has started to develop tools and produce data sets to de-orphanize transporters in the solute carrier protein (SLC) superfamily, thereby lowering the barrier for the scientific community to explore SLCs as an attractive drug target class.
Journal ArticleDOI
The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research
Joseline Ratnam,Barbara Zdrazil,Daniela Digles,Emiliano Cuadrado-Rodriguez,Jean-Marc Neefs,Hannah Tipney,Ronny Siebes,Andra Waagmeester,Glyn Bradley,Chau Han Chau,Lars Richter,José Brea,Chris T. Evelo,Edgar Jacoby,Stefan Senger,María Isabel Loza,Gerhard F. Ecker,Christine Chichester +17 more
TL;DR: The example workflows presented illustrate how the Open PHACTS Discovery Platform can be used to exploit existing knowledge and generate new hypotheses in the process of drug discovery.
Journal ArticleDOI
Self-Organizing Maps for In Silico Screening and Data Visualization.
Daniela Digles,Gerhard F. Ecker +1 more
TL;DR: The use of self‐organizing maps for in silico screening and for clustering and visualisation of large datasets are focused on.