P
Pieter Giesbertz
Researcher at Technische Universität München
Publications - 31
Citations - 1756
Pieter Giesbertz is an academic researcher from Technische Universität München. The author has contributed to research in topics: Amino acid & Chemistry. The author has an hindex of 15, co-authored 27 publications receiving 1255 citations. Previous affiliations of Pieter Giesbertz include Maastricht University.
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Journal ArticleDOI
WikiPathways : a multifaceted pathway database bridging metabolomics to other omics research
Denise Slenter,Martina Kutmon,Kristina Hanspers,Anders Riutta,Jacob Windsor,Nuno Nunes,Jonathan Mélius,Elisa Cirillo,Susan L. Coort,Daniela Digles,Friederike Ehrhart,Pieter Giesbertz,Marianthi Kalafati,Marvin Martens,Ryan A. Miller,Kozo Nishida,Linda Rieswijk,Andra Waagmeester,Lars M. T. Eijssen,Lars M. T. Eijssen,Chris T. Evelo,Alexander R. Pico,Egon Willighagen +22 more
TL;DR: There is a doubling of the number of annotated metabolite nodes in WikiPathways and an OpenAPI documentation of the authors' web services and the FAIR annotation of resources to increase the interoperability of the knowledge encoded in these pathways and experimental omics data.
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Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies
Marynka Ulaszewska,Christoph H. Weinert,Alessia Trimigno,Reto Portmann,Cristina Andres Lacueva,René Badertscher,Lorraine Brennan,Carl Brunius,Achim Bub,Francesco Capozzi,Marta Cialiè Rosso,Chiara Cordero,Hannelore Daniel,Stéphanie Durand,Bjoern Egert,Paola G. Ferrario,Edith J. M. Feskens,Pietro Franceschi,Mar Garcia-Aloy,Franck Giacomoni,Pieter Giesbertz,Raúl González-Domínguez,Kati Hanhineva,Lieselot Hemeryck,Joachim Kopka,Sabine E. Kulling,Rafael Llorach,Claudine Manach,Fulvio Mattivi,Carole Migné,Linda H. Münger,Beate Ott,Gianfranco Picone,Grégory Pimentel,Estelle Pujos-Guillot,Samantha Riccadonna,Manuela J. Rist,Caroline Rombouts,Josep Rubert,Thomas Skurk,Pedapati S. C. Sri Harsha,Lieven Van Meulebroek,Lynn Vanhaecke,Rosa Vázquez-Fresno,David S. Wishart,Guy Vergères +45 more
TL;DR: A methodological description of nutritional metabolomics is provided that reflects on the state-of-the-art techniques used in the laboratories of the Food Biomarker Alliance as well as points of reflections to harmonize this field.
Journal ArticleDOI
Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes
Pieter Giesbertz,Inken Padberg,Dietrich Rein,Josef Ecker,Anja S. Höfle,Britta Spanier,Hannelore Daniel +6 more
TL;DR: By studying mice with metabolite signatures that resemble obesity and diabetes in humans, this work has found new metabolite entities for validation in appropriate human cohorts and revealed their possible tissue of origin.
Journal ArticleDOI
Mitochondrial function controls intestinal epithelial stemness and proliferation
Emanuel Berger,Eva Rath,Detian Yuan,Nadine Waldschmitt,Sevana Khaloian,Michael Allgäuer,Ori Staszewski,Elena M. Lobner,Theresa Schöttl,Pieter Giesbertz,Olivia I. Coleman,Marco Prinz,Achim Weber,Markus Gerhard,Martin Klingenspor,Klaus-Peter Janssen,Mathias Heikenwalder,Dirk Haller +17 more
TL;DR: Compensatory hyperproliferation of HSP60+ escaper stem cells suggests paracrine release of WNT-related factors from H SP60-deficient, functionally impaired IEC to be pivotal in the control of the proliferative capacity of the stem cell niche.
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Branched-chain amino acids as biomarkers in diabetes.
TL;DR: Understanding the mechanisms and putative causalities in the alterations in BCAA levels as found in obesity, metabolic syndrome and diabetes is crucial for any intervention options but also for the use of BCAA and derivatives as biomarkers in clinical routine.