D
Dapa A. Diallo
Researcher at University of Bamako
Publications - 103
Citations - 4569
Dapa A. Diallo is an academic researcher from University of Bamako. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 33, co-authored 97 publications receiving 4225 citations. Previous affiliations of Dapa A. Diallo include University of Maryland, Baltimore & National Institutes of Health.
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Journal ArticleDOI
Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting
J. Alexandra Rowe,Ian Handel,Mahamadou A. Thera,Anne-Marie Deans,Kirsten E. Lyke,Abdoulaye K. Kone,Dapa A. Diallo,Ahmed Raza,Oscar Kai,Kevin Marsh,Christopher V. Plowe,Ogobara K. Doumbo,Joann M. Moulds +12 more
TL;DR: In a matched case-control study of 567 Malian children, the authors found that group O was present in only 21% of severe malaria cases compared with 44-45% of uncomplicated malaria controls and healthy controls.
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A field trial to assess a blood-Stage malaria vaccine
Mahamadou A. Thera,Ogobara K. Doumbo,Drissa Coulibaly,Matthew B. Laurens,Amed Ouattara,Abdoulaye K. Kone,Ando B. Guindo,Karim Traore,Idrissa Traore,Bourema Kouriba,Dapa A. Diallo,Issa Diarra,Modibo Daou,Amagana Dolo,Youssouf Tolo,Mahamadou S. Sissoko,Amadou Niangaly,Mady Sissoko,Shannon Takala-Harrison,Kirsten E. Lyke,Yukun Wu,William C. Blackwelder,Olivier Godeaux,Johan Vekemans,Marie-Claude Dubois,W. Ripley Ballou,Joe Cohen,Darby J. S. Thompson,Tina J. T. Dube,Lorraine Soisson,Carter L. Diggs,Brent House,David E. Lanar,Sheetij Dutta,D. Gray Heppner,Christopher V. Plowe +35 more
TL;DR: The malaria vaccine did not provide significant protection against clinical malaria, but on the basis of secondary results, it may have strain-specific efficacy.
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X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria.
TL;DR: The results indicate that the uniform state of G6PD deficiency in hemizygous male children conferred significant protection against severe, life-threatening malaria, and that it may have likewise protected homozygous female children, and give fresh perspectives on malaria protection by G6 PD deficiency as an X-linked trait.
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Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin
Rushina Cholera,Nathaniel J. Brittain,Mark R. Gillrie,Tatiana M. Lopera-Mesa,Seidina A. S. Diakite,Takayuki Arie,Michael Krause,Aldiouma Guindo,Abby Tubman,Hisashi Fujioka,Dapa A. Diallo,Ogobara K. Doumbo,May Ho,Thomas E. Wellems,Rick M. Fairhurst +14 more
TL;DR: Findings identify a mechanism of protection for HbS that has features in common with that of hemoglobin C (HbC).
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Abnormal display of PfEMP-1 on erythrocytes carrying haemoglobin C may protect against malaria
Rick M. Fairhurst,Dror I. Baruch,Nathaniel J. Brittain,Graciela R. Ostera,John S Wallach,Holly L Hoang,Karen Hayton,Aldiouma Guindo,Morris O. Makobongo,Owen Schwartz,A. Tounkara,Ogobara K. Doumbo,Dapa A. Diallo,Hisashi Fujioka,May Ho,Thomas E. Wellems +15 more
TL;DR: Haemoglobin C might protect against malaria by reducing PfEMP-1-mediated adherence of parasitized erythrocytes, thereby mitigating the effects of their sequestration in the microvasculature.