D
Dariusz M. Kowalski
Researcher at Curie Institute
Publications - 161
Citations - 12935
Dariusz M. Kowalski is an academic researcher from Curie Institute. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 25, co-authored 129 publications receiving 7930 citations.
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Journal ArticleDOI
Phase II Study of Roniciclib in Combination with Cisplatin/Etoposide or Carboplatin/Etoposide as First-Line Therapy in Patients with Extensive-Disease Small Cell Lung Cancer.
Martin Reck,Leora Horn,Silvia Novello,Fabrice Barlesi,Istvan Albert,E. Juhasz,Dariusz M. Kowalski,Gilles Robinet,Jacques Cadranel,Paolo Bidoli,John Chung,Arno Fritsch,Uta Drews,Andrea Wagner,Ramaswamy Govindan +14 more
TL;DR: Roniciclib combined with chemotherapy demonstrated an unfavorable risk‐benefit profile in patients with extensive‐disease SCLC, and the study was prematurely terminated.
Journal Article
EGFR mutation testing on cytological and histological samples in non-small cell lung cancer: a Polish, single institution study and systematic review of European incidence
Anna Szumera-Ciećkiewicz,Włodzimierz T. Olszewski,Andrzej Tysarowski,Dariusz M. Kowalski,Maciej Głogowski,Maciej Krzakowski,Janusz A. Siedlecki,Michał Wągrodzki,Monika Prochorec-Sobieszek +8 more
TL;DR: This is the first, single institution study that estimates the EGFR mutation incidence in the Polish population and finds the strongest clinicopathological correlation with the EGfr mutation was found for histological type, gender, and FISH positive result.
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The efficacy of EGFR gene mutation testing in various samples from non-small cell lung cancer patients: a multicenter retrospective study.
Paweł Krawczyk,Rodryg Ramlau,Joanna Chorostowska-Wynimko,Tomasz Powrózek,Marzena Anna Lewandowska,Janusz Limon,Bartosz Wasąg,Juliusz Pankowski,Jerzy Kozielski,Ewa Kalinka-Warzocha,Aleksandra Szczesna,Kamila Wojas-Krawczyk,Michal Skronski,Rafal Dziadziuszko,Paulina Jaguś,Ewelina Antoszewska,Justyna Szumiło,Bożena Jarosz,Aldona Woźniak,Wojciech Jóźwicki,Wojciech Dyszkiewicz,Monika Pasieka-Lis,Dariusz M. Kowalski,Maciej Krzakowski,Jacek Jassem,Janusz Milanowski +25 more
TL;DR: Cytological and small biopsy samples with low content of tumor cells and specimens from metastatic lesions are a sufficient source for EGFR mutation testing in NSCLC patients and the incidence of EGFR gene mutations was similar to those reported in other Caucasian populations.
Journal ArticleDOI
Cardiovascular Complications of Systemic Therapy in Non-Small-Cell Lung Cancer.
TL;DR: awareness of all possible cardiovascular complications in NSCLC encourages vigilance in early diagnostics and treatment, and Cytotoxic agents and anti-VEGF inhibitors mainly cause vascular complications, including venous or arterial TE.
Journal ArticleDOI
Pembrolizumab (pembro) plus platinum-based chemotherapy (chemo) in NSCLC with brain metastases: Pooled analysis of KEYNOTE-021, 189, and 407
Steven Francis Powell,D. Rodriguez Abreu,Corey J. Langer,Ali Tafreshi,Luis Paz-Ares,H.-G. Kopp,J. Rodríguez-Cid,Dariusz M. Kowalski,Ying Cheng,Takayasu Kurata,Mark M. Awad,J. Lin,Bin Zhao,M.C. Pietanza,Bilal Piperdi,M.C. Garassino +15 more
TL;DR: Pembro plus chemo provided clinical benefit for pts with NSCLC pts, regardless of presence/absence of stable brain metastases, and the toxicity profile was manageable.