D
David C. Page
Researcher at Massachusetts Institute of Technology
Publications - 523
Citations - 47344
David C. Page is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Y chromosome & X chromosome. The author has an hindex of 110, co-authored 509 publications receiving 44119 citations. Previous affiliations of David C. Page include Hennepin County Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Health Profiles of Mosaic Versus Non-mosaic FMR1 Premutation Carrier Mothers of Children With Fragile X Syndrome
Marsha R. Mailick,Arezoo Movaghar,Jinkuk Hong,Jan S. Greenberg,Leann Smith DaWalt,Lili Zhou,Jonathan Jackson,Paul J. Rathouz,Mei W. Baker,Murray H. Brilliant,Murray H. Brilliant,David C. Page,Elizabeth Berry-Kravis +12 more
TL;DR: Although only 14 premutation carrier mothers in the present sample also had a small population of full mutation cells, their profile of comparatively better health, mental health, and executive functioning was unexpected, and should prompt additional research on larger numbers of participants with more extensive phenotyping to confirm the clinical correlates of low-level full mutation mosaicism in premutation carriers.
Journal ArticleDOI
Rps4 maps near the inactivation center on the mouse X chromosome
Renata M.J. Hamvas,Andrew R. Zinn,Andrew R. Zinn,J. T. Keer,Elizabeth M. C. Fisher,Peggy Beer-Romero,Peggy Beer-Romero,Stephen D.M. Brown,David C. Page,David C. Page +9 more
TL;DR: Genetic mapping utilizing interspecific mouse backcrosses and the intron-specific probe demonstrates that Rps4 maps close to the Phka locus on the mouse X chromosome and in the vicinity of the X-inactivation center.
Book ChapterDOI
A Machine-Learning-Based Drug Repurposing Approach Using Baseline Regularization.
Zhaobin Kuang,Yujia Bao,James A. Thomson,Michael D. Caldwell,Peggy L. Peissig,Ron Stewart,Rebecca Willett,David C. Page +7 more
TL;DR: The baseline regularization model for computational drug repurposing using electronic health records (EHRs) is presented, which uses statistical relationships between the occurrences of prescriptions of some particular drugs and the increase or the decrease in the values ofSome particular numeric physical measurements to identify potential repurpose opportunities.
Journal ArticleDOI
Regional assignments of three polymorphic DNA segments on human chromosome 15.
J. E. Brissenden,David C. Page,B de Martinville,J. Trowsdale,David Botstein,Uta Francke,J. M. Lalouel +6 more
TL;DR: In situ hybridization of pDP151 to EcoRI‐digested DNAs from 21 Chinese hamster × human hybrid cell clones containing different subsets of human chromosomes demonstrated cosegregation of the 9 and 11 kb EcoRI fragments with human chromosome 15.