D
David C. Page
Researcher at Massachusetts Institute of Technology
Publications - 523
Citations - 47344
David C. Page is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Y chromosome & X chromosome. The author has an hindex of 110, co-authored 509 publications receiving 44119 citations. Previous affiliations of David C. Page include Hennepin County Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Retinoic acid regulates sex-specific timing of meiotic initiation in mice.
TL;DR: In this paper, the authors examined the mechanism underlying the sex-specific timing of Stra8 expression and meiotic initiation in mice and showed that signaling by retinoic acid (RA), an active derivative of vitamin A, is required for Stra8expression and thereby meiosis initiation in embryonic ovaries.
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A comprehensive genetic map of the mouse genome
William F. Dietrich,Joyce C. Miller,Robert G. Steen,Mark Merchant,Deborah Damron-Boles,Zeeshan Husain,Robert Dredge,Mark J. Daly,Kimberly A. Ingalls,Tara J. O'Connor,Cheryl A. Evans,Margaret M. DeAngelis,David M. Levinson,Leonid Kruglyak,Nathan Goodman,Neal G. Copeland,Nancy A. Jenkins,Trevor Hawkins,Lincoln Stein,David C. Page,Eric S. Lander +20 more
TL;DR: The final report of the concerted effort to produce a dense genetic map of the laboratory mouse contains 7,377 genetic markers, consisting of 6,580 highly informative simple sequence length polymorphisms integrated with 797 restriction fragmentlength polymorphisms in mouse genes.
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An STS-Based Map of the Human Genome
Thomas J. Hudson,Lincoln D. Stein,Sebastian S. Gerety,Junli Ma,Andrew B. Castle,James Silva,Donna K. Slonim,Rafael Baptista,Leonid Kruglyak,Shu-Hua Xu,Xintong Hu,Angela M. E. Colbert,Carl Rosenberg,Mary Pat Reeve-Daly,Steve Rozen,Lester Hui,Xiaoyun Wu,Christina Vestergaard,Kimberly M. Wilson,Jane S. Bae,Shanak Maitra,Soula Ganiatsas,Cheryl A. Evans,Margaret M. DeAngelis,Kimberly A. Ingalls,Robert Nahf,Lloyd T. Horton,Michele Oskin Anderson,Alville Collymore,Wenjuan Ye,Vardouhie Kouyoumjian,Irena S. Zemsteva,James P. Tam,Richard Devine,Dorothy F. Courtney,Michelle Turner Renaud,Huy Nguyen,Tara J. O'Connor,Cécile Fizames,Sabine Fauré,Gabor Gyapay,Colette Dib,Jean Morissette,James B. Orlin,Bruce W. Birren,Nathan Goodman,Jean Weissenbach,Trevor Hawkins,Simon J. Foote,David C. Page,Eric S. Lander +50 more
TL;DR: A physical map has been constructed of the human genome containing 15,086 sequence-tagged sites (STSs), with an average spacing of 199 kilobases, anchored by the radiation hybrid and genetic maps.
Journal ArticleDOI
The sex-determining region of the human Y chromosome encodes a finger protein
David C. Page,Rebecca Mosher,Elizabeth M. Simpson,Elizabeth M. C. Fisher,Graeme Mardon,Jonathan R. Pollack,Barbara McGillivray,Albert de la Chapelle,Laura G. Brown +8 more
TL;DR: The possibility that the Y-encoded finger protein is the testis-determining factor is discussed, and models of sex determination accommodating the finding of a related locus on the X chromosome are proposed.
Journal ArticleDOI
Functional coherence of the human Y chromosome.
Bruce T. Lahn,David C. Page +1 more
TL;DR: A systematic search of the nonrecombining region of the human Y chromosome (NRY) identified 12 novel genes or families, 10 with full-length complementary DNA sequences, which may account for infertility among men with Y deletions.