D
David C. Page
Researcher at Massachusetts Institute of Technology
Publications - 523
Citations - 47344
David C. Page is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Y chromosome & X chromosome. The author has an hindex of 110, co-authored 509 publications receiving 44119 citations. Previous affiliations of David C. Page include Hennepin County Medical Center & University of California, Los Angeles.
Papers
More filters
Journal ArticleDOI
Sex-determining genes on mouse autosomes identified by linkage analysis of C57BL/6J-YPOS sex reversal.
Eva M. Eicher,L L Washburn,Nicholas J. Schork,B K Lee,E P Shown,Xiaoling Xu,Robert Dredge,M J Pringle,David C. Page +8 more
TL;DR: The number and chromosomal location of autosomal and X-linked genes that cause sex reversal in C57BL/6J (B6) mice carrying a Y chromosome of Mus domesticus poschiavinus origin are determined and it is suggested that B6 alleles at these loci predispose XYPOS fetuses to ovarian tissue development.
Journal ArticleDOI
Two Closely Related Human Nuclear Export Factors Utilize Entirely Distinct Export Pathways
TL;DR: It is demonstrated that NXF3, a human RNA binding protein related to TAP, lacks a carboxy-terminal domain yet retains the ability to export tethered RNA transcripts and to shuttle between the nucleus and the cytoplasm.
Journal ArticleDOI
A Bayesian network approach to operon prediction.
TL;DR: This work presents a probabilistic approach to predicting operons using Bayesian networks and evaluates this approach on the Escherichia coli K-12 genome where results indicate it is able to identify over 78% of its operons at a 10% false positive rate.
Journal ArticleDOI
AZFc Deletions and Spermatogenic Failure: A Population-Based Survey of 20,000 Y Chromosomes
Steven G. Rozen,Janet D. Marszalek,Janet D. Marszalek,Kathryn Irenze,Helen Skaletsky,Helen Skaletsky,Laura G. Brown,Laura G. Brown,Robert D. Oates,Sherman J. Silber,Kristin G. Ardlie,David C. Page,David C. Page +12 more
TL;DR: In this paper, the authors found that deletions involving the Y chromosome's AZFc region are the most common known genetic cause of severe spermatogenic failure (SSF).
Journal ArticleDOI
Men With Infertility Caused by AZFc Deletion Can Produce Sons by Intracytoplasmic Sperm Injection, but Are Likely to Transmit the Deletion and Infertility
TL;DR: Three unrelated men in whom azoospermia or severe oligozoospermia was caused by de-novo AZFc deletions, and who produced sons by intracytoplasmic sperm injection (ICSI) are reported, are likely to be infertile as adults.