D
David Elashoff
Researcher at University of California, Los Angeles
Publications - 519
Citations - 28932
David Elashoff is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 70, co-authored 479 publications receiving 23935 citations. Previous affiliations of David Elashoff include City of Hope National Medical Center & Stanford University.
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Journal ArticleDOI
PD-1 blockade induces responses by inhibiting adaptive immune resistance
Paul C. Tumeh,Christina L. Harview,Jennifer H. Yearley,I. Peter Shintaku,Emma Taylor,Lidia Robert,Bartosz Chmielowski,Marko Spasic,Gina Henry,Voicu Ciobanu,Alisha N. West,Manuel Carmona,Christine Kivork,Elizabeth Seja,Grace Cherry,Antonio Gutierrez,Tristan Grogan,Christine Mateus,Gorana Tomasic,John A. Glaspy,Ryan O. Emerson,Harlan Robins,Robert H. Pierce,David Elashoff,Caroline Robert,Antoni Ribas +25 more
TL;DR: It is shown that pre-existing CD8+ T cells distinctly located at the invasive tumour margin are associated with expression of the PD-1/PD-L1 immune inhibitory axis and may predict response to therapy.
Journal ArticleDOI
Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma
Mark B. Faries,John F. Thompson,Alistair J. Cochran,Robert H.I. Andtbacka,Nicola Mozzillo,Jonathan S. Zager,Tiina Jahkola,Tawnya L. Bowles,Alessandro Testori,Peter D. Beitsch,Harald J. Hoekstra,Marc Moncrieff,Christian Ingvar,Michel W.J.M. Wouters,Michael S. Sabel,Edward A. Levine,Doreen M. Agnese,Michael A. Henderson,Reinhard Dummer,Carlo Riccardo Rossi,Rogerio I. Neves,Steven D. Trocha,Frances C. Wright,David R. Byrd,Maurice Matter,Eddy Hsueh,Alastair MacKenzie-Ross,Douglas B. Johnson,Patrick Terheyden,Adam C. Berger,Tara L. Huston,Jeffrey D. Wayne,B. Mark Smithers,Heather B. Neuman,Schlomo Schneebaum,Jeffrey E. Gershenwald,Charlotte E. Ariyan,Darius C. Desai,Lisa K. Jacobs,Kelly M. McMasters,Anja Gesierich,Peter Hersey,Steven D. Bines,John M. Kane,Richard J. Barth,Gregory McKinnon,Jeffrey M. Farma,Erwin S. Schultz,Sergi Vidal-Sicart,Richard A. Hoefer,James M. Lewis,Randall P. Scheri,Mark C. Kelley,Omgo E. Nieweg,R. Dirk Noyes,Dave S.B. Hoon,He-Jing Wang,David Elashoff,Robert Elashoff +58 more
TL;DR: Immediate completion lymph‐node dissection increased the rate of regional disease control and provided prognostic information but did not increase melanoma‐specific survival among patients with melanoma and sentinel‐node metastases.
Journal ArticleDOI
Salivary microRNA: Discovery, Characterization, and Clinical Utility for Oral Cancer Detection
Noh Jin Park,Hui Zhou,David Elashoff,Bradley S. Henson,Dragana A. Kastratović,Elliot Abemayor,David T.W. Wong +6 more
TL;DR: Both whole and supernatant saliva of healthy controls contained dozens of miRNA, and similar to saliva mRNAs, these miRNAs are stable and can be used for oral cancer detection.
Journal ArticleDOI
Salivary Transcriptome Diagnostics for Oral Cancer Detection
Yang Li,Maie A. St. John,Xiaofeng Zhou,Yong Kim,Uttam K. Sinha,Richard C.K. Jordan,David W. Eisele,Elliot Abemayor,David Elashoff,No-Hee Park,David T.W. Wong +10 more
TL;DR: The utility of salivary transcriptome diagnostics is successfully demonstrated in this study for oral cancer detection and could be exploited to a robust, high-throughput, and reproducible tool for early cancer detection.
Journal ArticleDOI
Propionibacterium acnes Strain Populations in the Human Skin Microbiome Associated with Acne
Sorel Fitz-Gibbon,Shuta Tomida,Bor Han Chiu,Lin Nguyen,Christine Du,Minghsun Liu,David Elashoff,Marie C. Erfe,Anya Loncaric,Jenny Kim,Jenny Kim,Robert L. Modlin,Jeff F. Miller,Erica Sodergren,Noah Craft,George M. Weinstock,Huiying Li +16 more
TL;DR: This study demonstrates a previously unreported paradigm of commensal strain populations that could explain the pathogenesis of human diseases and underscores the importance of strain level analysis of the human microbiome to define the role of Commensals in health and disease.