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David M. Hwang
Researcher at Sunnybrook Health Sciences Centre
Publications - 184
Citations - 9146
David M. Hwang is an academic researcher from Sunnybrook Health Sciences Centre. The author has contributed to research in topics: Lung transplantation & Lung. The author has an hindex of 48, co-authored 179 publications receiving 7241 citations. Previous affiliations of David M. Hwang include Toronto General Hospital & University Health Network.
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Journal ArticleDOI
Prognostic factors for cure, recurrence and long-term survival after surgical resection of thymoma
Najib Safieddine,Geoffrey Liu,Kris Cuningham,Tsao Ming,David M. Hwang,Anthony Brade,Andrea Bezjak,Stefan Fischer,Wei Xu,Sassan Azad,Marcelo Cypel,Gail Darling,Kazu Yasufuku,Andrew Pierre,Marc de Perrot,Thomas K. Waddell,Shaf Keshavjee +16 more
TL;DR: Only Masaoka stage and tumor size were associated with statistically significant risk of recurrence on multivariate analysis and Aggressive resection of recurrent disease yielded excellent long-term results.
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Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis.
Shawn T. Clark,Julio Diaz Caballero,Mary Cheang,Bryan Coburn,Pauline W. Wang,Sylva L. Donaldson,Yu Zhang,Mingyao Liu,Shaf Keshavjee,Yvonne C. W. Yau,Valerie Waters,D. Elizabeth Tullis,David S. Guttman,David M. Hwang +13 more
TL;DR: The findings confirm that the P. aeruginosa population in chronic CF lung infections is highly dynamic, and that intra-sample phenotypic diversity is underestimated if only one or few colonies are analyzed per sample.
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Activation of P2X7 Receptor by ATP Plays an Important Role in Regulating Inflammatory Responses during Acute Viral Infection
Benjamin H. Lee,David M. Hwang,David M. Hwang,Nades Palaniyar,Sergio Grinstein,Dana J. Philpott,Jim Hu +6 more
TL;DR: Results indicate that ATP, released during viral infection, is an important inflammatory regulator that activates the inflammasome pathway and regulates inflammatory responses.
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FISH assay development for the detection of p16/CDKN2A deletion in malignant pleural mesothelioma
Catherine T-S Chung,Gilda da Cunha Santos,David M. Hwang,Olga Ludkovski,Melania Pintilie,Jeremy A. Squire,Ming-Sound Tsao +6 more
TL;DR: Distinction between benign and malignant mesothelial proliferations can be diagnostically challenging and FISH for p16/CDKN2A deletion is a useful test for confirming the diagnosis of MPM.
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The early responses of VEGF and its receptors during acute lung injury: implication of VEGF in alveolar epithelial cell survival
Marco Mura,Bing Han,Cristiano Feijó Andrade,Rashmi Seth,David M. Hwang,Thomas K. Waddell,Shaf Keshavjee,Mingyao Liu +7 more
TL;DR: V EGF may have dual roles in ALI: early release of VEGF may increase pulmonary vascular permeability; reduced expression of V EGF and VEGFR-1 in lung tissue may contribute to the death of alveolar epithelial cells.