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David M. Hwang
Researcher at Sunnybrook Health Sciences Centre
Publications - 184
Citations - 9146
David M. Hwang is an academic researcher from Sunnybrook Health Sciences Centre. The author has contributed to research in topics: Lung transplantation & Lung. The author has an hindex of 48, co-authored 179 publications receiving 7241 citations. Previous affiliations of David M. Hwang include Toronto General Hospital & University Health Network.
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Journal ArticleDOI
A feasibility study evaluating Surgery for Mesothelioma After Radiation Therapy: the "SMART" approach for resectable malignant pleural mesothelioma.
B.C. John Cho,Ron Feld,Natasha B. Leighl,Isabelle Opitz,Masaki Anraku,Ming-Sound Tsao,David M. Hwang,Andrew Hope,Marc de Perrot +8 more
TL;DR: This innovative protocol presents encouraging results and supports future studies looking at long-term outcome in patients with epithelial subtypes, as SMART is feasible in resectable MPM patients.
Journal ArticleDOI
Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre- and post-lung transplantation in the pig.
Jonathan C. Yeung,D. Wagnetz,Marcelo Cypel,M. Rubacha,Terumoto Koike,Yi-Min Chun,Jim Hu,Thomas K. Waddell,David M. Hwang,Mingyao Liu,Shaf Keshavjee +10 more
TL;DR: Ex vivo delivery of adenoviral gene therapy to the donor lung is superior to in vivo delivery in that it leads to less vector-associated inflammation and provides superior post-transplant lung function.
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Nanoparticle exposure in animals can be visualized in the skin and analysed via skin biopsy
TL;DR: It is shown that mice intravenously administered with high doses of gold nanoparticles have visibly blue skin while quantum dot-treated mice emit green, yellow, or red fluorescence after ultraviolet excitation, and elemental analysis of excised skin correlates with the injected dose and nanoparticle accumulation in the liver and spleen.
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Targeted cell replacement with bone marrow cells for airway epithelial regeneration
Amy P. Wong,Andre E. Dutly,Adrian G. Sacher,Haeyul Lee,David M. Hwang,Mingyao Liu,Shaf Keshavjee,Jim Hu,Thomas K. Waddell +8 more
TL;DR: The combination of mild airway injury (naphthalene-induced) as a conditioning regimen to direct the site of BMC localization and transtracheal delivery of short-term cultured BMC enhances airway localization and adoption of an epithelial-like phenotype.
Journal ArticleDOI
The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
John C Mavropoulos,W. Cooper Buschemeyer,Alok K. Tewari,Dmitriy Rokhfeld,Michael Pollak,Yunhua Zhao,Phillip G. Febbo,Pinchas Cohen,David M. Hwang,Gayathri R. Devi,Wendy Demark-Wahnefried,Eric C. Westman,Bercedis L. Peterson,Salvatore V. Pizzo,Stephen J. Freedland +14 more
TL;DR: The results support further preclinical exploration of carbohydrate restriction in prostate cancer and possibly warrant pilot or feasibility testing in humans.