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David M. Hwang
Researcher at Sunnybrook Health Sciences Centre
Publications - 184
Citations - 9146
David M. Hwang is an academic researcher from Sunnybrook Health Sciences Centre. The author has contributed to research in topics: Lung transplantation & Lung. The author has an hindex of 48, co-authored 179 publications receiving 7241 citations. Previous affiliations of David M. Hwang include Toronto General Hospital & University Health Network.
Papers
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The Tie2-agonist Vasculotide rescues mice from influenza virus
Susan M. Armstrong,Changsen Wang,David M. Hwang,Howard Leong-Poi,Andrew Advani,Suzanne L. Advani,Haibo Zhang,Katalin Szászi,Arata Tabuchi,Wolfgang M. Kuebler,Paul Van Slyke,Daniel J. Dumont,Warren L. Lee +12 more
TL;DR: In this article, a Tie2agonist tetrameric peptide Vasculotide was used to enhance lung endothelial barrier integrity to improve the outcome of severe influenza infection, even after 72 hours after infection.
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Ultrasound-guided transfection of claudin-5 improves lung endothelial barrier function in lung injury without impairing innate immunity.
Rajiv Sanwal,Victoria Mintsopoulos,Mihails Ditmans,Elyse Latreille,Siavash Ghaffari,Negar Khosraviani,Raffi Karshafian,Howard Leong-Poi,David M. Hwang,Laurent Brochard,Alberto Goffi,Arthur S. Slutsky,Warren L. Lee +12 more
TL;DR: In this article , the authors used thoracic ultrasound in combination with intravenous microbubbles (USMB) to achieve regional gene transfection in injured lung regions and improve endothelial barrier function.
Posted ContentDOI
Predictive modeling of antibiotic eradication therapy success for new-onset Pseudomonas aeruginosa pulmonary infections in children with cystic fibrosis
Lucía Graña-Miraglia,Nadia P. Morales-Lizcano,Pauline W. Wang,David M. Hwang,Yvonne C. W. Yau,Valerie Waters,David S. Guttman +6 more
TL;DR: In this paper , the authors used random forest machine learning models to predict AET outcomes based on pathogen genomic data and found that their best model could predict treatment outcome with an accuracy of 0.87 for a holdout test dataset.
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Lung allograft standardized histological analysis (LASHA) template: A research consensus proposal.
Fiorella Calabrese,Anja C. Roden,Elizabeth N. Pavlisko,Francesca Lunardi,Desley Neil,Benjamin Adam,David M. Hwang,Martin Goddard,Gerald J. Berry,Marina Ivanovic,Jan H. von der Thüsen,Laure Gibault,Chieh Yu Lin,Katharina Wassilew,C.R. Glass,Glen P. Westall,Adriana Zeevi,Deborah Levine,Antoine Roux +18 more
TL;DR: The Lung Allograft Standardized Histological Analysis (LASHA) template as mentioned in this paper was created by experts in lung transplantation including pathologists, pulmonologists, immunologists.