G
Geoffrey Liu
Researcher at Princess Margaret Cancer Centre
Publications - 537
Citations - 23657
Geoffrey Liu is an academic researcher from Princess Margaret Cancer Centre. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 67, co-authored 534 publications receiving 19510 citations. Previous affiliations of Geoffrey Liu include Mount Sinai Hospital, Toronto & Harvard University.
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Journal ArticleDOI
Ceritinib in ALK-Rearranged Non–Small-Cell Lung Cancer
Alice T. Shaw,Dong Wan Kim,Ranee Mehra,Daniel Shao-Weng Tan,Enriqueta Felip,Laura Q.M. Chow,D. Ross Camidge,Johan Vansteenkiste,Sunil Sharma,Tommaso De Pas,Gregory J. Riely,Benjamin Solomon,Juergen Wolf,Michael Thomas,Martin Schuler,Martin Schuler,Geoffrey Liu,Armando Santoro,Yvonne Y. Lau,Meredith Goldwasser,Anthony Boral,Jeffrey A. Engelman +21 more
TL;DR: Ceritinib was highly active in patients with advanced, ALK-rearranged NSCLC, including those who had had disease progression during crizotinib treatment, regardless of the presence of resistance mutations in ALK.
Journal ArticleDOI
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
Rayjean J. Hung,James McKay,Valerie Gaborieau,Paolo Boffetta,Mia Hashibe,David Zaridze,Anush Mukeria,Neonilia Szeszenia-Dabrowska,Jolanta Lissowska,Peter Rudnai,Eleonora Fabianova,Dana Mates,Vladimir Bencko,Lenka Foretova,Vladimir Janout,Chu Chen,Gary E. Goodman,John K. Field,Triantafillos Liloglou,George Xinarianos,Adrian Cassidy,John R. McLaughlin,Geoffrey Liu,Steven A. Narod,Hans E. Krokan,Frank Skorpen,Maiken Bratt Elvestad,Kristian Hveem,Lars J. Vatten,Jakob Linseisen,Françoise Clavel-Chapelon,Paolo Vineis,H. Bas Bueno-de-Mesquita,Eiliv Lund,Carmen Martinez,Sheila Bingham,Torgny Rasmuson,Pierre Hainaut,Elio Riboli,Wolfgang Ahrens,Simone Benhamou,Pagona Lagiou,Dimitrios Trichopoulos,Ivana Holcatova,Franco Merletti,Kristina Kjærheim,Antonio Agudo,Gary J. Macfarlane,Renato Talamini,Lorenzo Simonato,Ray Lowry,David I. Conway,Ariana Znaor,Claire M. Healy,Diana Zelenika,Anne Boland,Marc Delepine,Mario Foglio,Doris Lechner,Fumihiko Matsuda,Hélène Blanché,Ivo Gut,Simon Heath,Mark Lathrop,Paul Brennan +64 more
TL;DR: The results provide compelling evidence of a locus at 15q25 predisposing to lung cancer, and reinforce interest in nicotinic acetylcholine receptors as potential disease candidates and chemopreventative targets.
Journal ArticleDOI
Probability of Cancer in Pulmonary Nodules Detected on First Screening CT
Annette McWilliams,Martin C. Tammemägi,John R. Mayo,Heidi C. Roberts,Geoffrey Liu,Kam Soghrati,Kazuhiro Yasufuku,Simon Martel,Francis Laberge,Michel Gingras,S. Atkar-Khattra,Christine D. Berg,Kenneth R. Evans,Richard J. Finley,John Yee,John C. English,Paola Nasute,John R. Goffin,Serge Puksa,Lori Stewart,Scott Tsai,Michael R. Johnston,Daria Manos,Garth Nicholas,Glenwood D. Goss,Jean M. Seely,Kayvan Amjadi,Alain Tremblay,Paul Burrowes,Paul MacEachern,Rick Bhatia,Ming-Sound Tsao,Stephen Lam +32 more
TL;DR: Predictive tools based on patient and nodule characteristics can be used to accurately estimate the probability that lung nodules detected on baseline screening low-dose CT scans are malignant, according to a population-based prospective study.
Journal ArticleDOI
Patient preferences for oral versus intravenous palliative chemotherapy.
TL;DR: Patients with incurable cancer have a clear preference for oral CT, but are generally not willing to sacrifice efficacy for their preference.
Journal ArticleDOI
Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study
Robert Carreras-Torres,Mattias Johansson,Philip C Haycock,Kaitlin H Wade,Caroline L Relton,Richard M. Martin,Richard M. Martin,George Davey Smith,Demetrius Albanes,Melinda C. Aldrich,Angeline S. Andrew,Susanne M. Arnold,Heike Bickeböller,Stig E. Bojesen,Hans Brunnström,Jonas Manjer,Irene Brüske,Neil E. Caporaso,Chu Chen,David C. Christiani,W. Jay Christian,Jennifer A. Doherty,Eric J. Duell,John K. Field,Michael P.A. Davies,Michael W. Marcus,Gary E. Goodman,Kjell Grankvist,Aage Haugen,Yun-Chul Hong,Lambertus A. Kiemeney,Erik H.F.M. van der Heijden,Peter Kraft,Mikael Johansson,Stephen Lam,Maria Teresa Landi,Philip Lazarus,Loic Le Marchand,Geoffrey Liu,Olle Melander,Sungshim L. Park,Gad Rennert,Angela Risch,Eric B. Haura,Ghislaine Scelo,David Zaridze,Anush Mukeriya,Milan Savic,Jolanta Lissowska,Beata Swiatkowska,Vladimir Janout,Ivana Holcatova,Dana Mates,Matthew B. Schabath,Hongbing Shen,Adonina Tardón,M. Dawn Teare,Penella J. Woll,Ming-Sound Tsao,Xifeng Wu,Jian-Min Yuan,Rayjean J. Hung,Christopher I. Amos,James D. McKay,Paul Brennan +64 more
TL;DR: The results are consistent with a causal role of fasting insulin and low-density lipoprotein cholesterol in lung cancer etiology, as well as for BMI in squamous cell and small cell carcinoma, and the latter relation may be mediated by a previously unrecognized effect of obesity on smoking behavior.