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David Parkinson

Researcher at University of Plymouth

Publications -  301
Citations -  18694

David Parkinson is an academic researcher from University of Plymouth. The author has contributed to research in topics: Dark energy & Redshift. The author has an hindex of 62, co-authored 283 publications receiving 16221 citations. Previous affiliations of David Parkinson include Washington University in St. Louis & Sheffield Hallam University.

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Journal ArticleDOI

Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy.

TL;DR: High-dose IL-2 appears to benefit some patients with metastatic renal cell carcinoma by producing durable CRs or PRs, despite severe acute treatment-associated toxicities, and should be considered for initial therapy of patients with appropriately selected metastatic carcinoma.
Book ChapterDOI

Model selection and multi-model inference

TL;DR: In this paper, the authors focus on the choice of model and the range of values of the parameters which are compatible with the data, which is the statistical problem of model comparison or model selection.
Journal ArticleDOI

Retinoids in cancer therapy.

TL;DR: The antitumor activity demonstrated for retinoids (especially RA) alone and in combination with other agents supports the need for targeted phase II trials to define the spectrum of responsive tumors and for laboratory studies to further delineate the biologic mechanisms associated with therapeutic responses.
Journal ArticleDOI

EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting

TL;DR: The results identify a link between Ephs and Sox proteins, providing a mechanism by which progenitor cells can translate environmental cues to orchestrate the formation of new tissue.