David R. Soll

TL;DR: There are significant expansions of cell wall, secreted and transporter gene families in pathogenic species, suggesting adaptations associated with virulence in Candida albicans species.

TL;DR: A second high-frequency switching system was identified in selected pathogenic strains in the dimorphic yeast Candida albicans, referred to as the white-opaque transition as mentioned in this paper.

TL;DR: The pathogenic yeast Candida albicans switches heritably and at high frequency between at least seven general phenotypes identified by colony morphology on agar, and the genetic basis of this newly discovered process and its possible role in Candida pathogenesis are considered.

TL;DR: The most dramatic switching system so far identified is the "white-opaque transition," which dramatizes the extraordinary effects switching can have on the budding cell phenotype, including the synthesis of opaque- specific antigens, the expression of white-specific and opaque-specific genes, and the genesis of unique cell wall structures.

TL;DR: An awareness is generated of the need to verify the efficacy of each DNA fingerprinting method for the level of genetic relatedness necessary to answer the epidemiological question posed, to use quantitative methods to analyze DNA fingerprint data, and to use computer-assisted DNA fingerprint analysis systems to analyze data.