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Kevin A. T. Silverstein
Researcher at University of Minnesota
Publications - 102
Citations - 8564
Kevin A. T. Silverstein is an academic researcher from University of Minnesota. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 38, co-authored 98 publications receiving 7646 citations. Previous affiliations of Kevin A. T. Silverstein include University of California, San Francisco & University of Texas Health Science Center at San Antonio.
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Journal ArticleDOI
The Medicago genome provides insight into the evolution of rhizobial symbioses
Nevin D. Young,Frédéric Debellé,Frédéric Debellé,Giles E. D. Oldroyd,René Geurts,Steven B. Cannon,Steven B. Cannon,Michael K. Udvardi,Vagner A. Benedito,Klaus F. X. Mayer,Jérôme Gouzy,Jérôme Gouzy,Heiko Schoof,Yves Van de Peer,Sebastian Proost,Douglas R. Cook,Blake C. Meyers,Manuel Spannagl,Foo Cheung,Stéphane De Mita,Vivek Krishnakumar,Heidrun Gundlach,Shiguo Zhou,Joann Mudge,Arvind K. Bharti,Jeremy D. Murray,Marina Naoumkina,Benjamin D. Rosen,Kevin A. T. Silverstein,Haibao Tang,Stephane Rombauts,Patrick X. Zhao,Peng Zhou,Valérie Barbe,Philippe Bardou,Philippe Bardou,Michael Bechner,Arnaud Bellec,Anne Berger,Hélène Bergès,Shelby L. Bidwell,Ton Bisseling,Ton Bisseling,Nathalie Choisne,Arnaud Couloux,Roxanne Denny,Shweta Deshpande,Xinbin Dai,Jeff J. Doyle,Anne Marie Dudez,Anne Marie Dudez,Andrew Farmer,Stéphanie Fouteau,Carolien Franken,Chrystel Gibelin,Chrystel Gibelin,John Gish,Steven A. Goldstein,Alvaro J. González,Pamela J. Green,Asis Hallab,Marijke Hartog,Axin Hua,Sean Humphray,Dong-Hoon Jeong,Yi Jing,Anika Jöcker,Steve Kenton,Dong-Jin Kim,Dong-Jin Kim,Kathrin Klee,Hongshing Lai,Chunting Lang,Shaoping Lin,Simone L. Macmil,Ghislaine Magdelenat,Lucy Matthews,Jamison McCorrison,Erin L. Monaghan,Jeong Hwan Mun,Jeong Hwan Mun,Fares Z. Najar,Christine Nicholson,Céline Noirot,Majesta O'Bleness,Charles Paule,Julie Poulain,Florent Prion,Florent Prion,Baifang Qin,Chunmei Qu,Ernest F. Retzel,Claire Riddle,Erika Sallet,Erika Sallet,Sylvie Samain,Nicolas Samson,Nicolas Samson,Iryna Sanders,Olivier Saurat,Olivier Saurat,Claude Scarpelli,Thomas Schiex,Béatrice Segurens,Andrew J. Severin,D. Janine Sherrier,Ruihua Shi,Sarah Sims,Susan R. Singer,Senjuti Sinharoy,Lieven Sterck,Agnès Viollet,Bing Bing Wang,Keqin Wang,Mingyi Wang,Xiaohong Wang,Jens Warfsmann,Jean Weissenbach,Doug White,James D. White,Graham B. Wiley,Patrick Wincker,Yanbo Xing,Limei Yang,Ziyun Yao,Fu Ying,Jixian Zhai,Liping Zhou,Antoine Zuber,Antoine Zuber,Jean Dénarié,Jean Dénarié,Richard A. Dixon,Gregory D. May,David C. Schwartz,Jane Rogers,Francis Quetier,Christopher D. Town,Bruce A. Roe +138 more
TL;DR: The draft sequence of the M. truncatula genome sequence is described, a close relative of alfalfa (Medicago sativa), a widely cultivated crop with limited genomics tools and complex autotetraploid genetics, which provides significant opportunities to expand al falfa’s genomic toolbox.
Journal ArticleDOI
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
Geraldine Butler,Matthew D. Rasmussen,Michael F. Lin,Michael F. Lin,Manuel A. S. Santos,Sharadha Sakthikumar,Carol A. Munro,Esther Rheinbay,Esther Rheinbay,Manfred Grabherr,Anja Forche,Jennifer L. Reedy,Ino Agrafioti,Martha B. Arnaud,Steven Bates,Alistair J. P. Brown,Sascha Brunke,Maria C. Costanzo,David A. Fitzpatrick,Piet W. J. de Groot,David Harris,Lois L. Hoyer,Bernhard Hube,Frans M. Klis,Chinnappa D. Kodira,Nicola Lennard,Mary E. Logue,Ronny Martin,Aaron M. Neiman,Elissavet Nikolaou,Michael A. Quail,Janet Quinn,Maria C. Santos,Florian F. Schmitzberger,Gavin Sherlock,Prachi Shah,Kevin A. T. Silverstein,Marek S. Skrzypek,David R. Soll,Rodney Staggs,Ian Stansfield,Michael P. H. Stumpf,Peter E. Sudbery,Thyagarajan Srikantha,Qiandong Zeng,Judith Berman,Matthew Berriman,Joseph Heitman,Neil A. R. Gow,Michael C. Lorenz,Bruce W. Birren,Manolis Kellis,Manolis Kellis,Christina A. Cuomo +53 more
TL;DR: There are significant expansions of cell wall, secreted and transporter gene families in pathogenic species, suggesting adaptations associated with virulence in Candida albicans species.
Journal ArticleDOI
Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines.
Yingming Li,Siu Chiu Chan,Lucas J. Brand,Tae Hyun Hwang,Kevin A. T. Silverstein,Scott M. Dehm +5 more
TL;DR: This study shows that cells with AR gene rearrangements expressing both full-length and AR-Vs are androgen independent and enzalutamide resistant, but selective knock-down of AR-V expression inhibited androgen-independent growth and restored responsiveness to androgens and antiandrogens.
Journal ArticleDOI
Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
Kevin A. T. Silverstein,William A. Moskal,Hank C. Wu,Beverly A. Underwood,Michelle A. Graham,Christopher D. Town,Kathryn A. VandenBosch +6 more
TL;DR: The identified genes include classes of defensins, thionins, lipid transfer proteins, and snakins, plus other protease inhibitors, pollen allergens, and uncharacterized gene families, and it is estimated that these classes of genes account for approximately 2-3% of the gene repertoire of each model species.
Journal ArticleDOI
A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer
Timothy K. Starr,Raha Allaei,Kevin A. T. Silverstein,Rodney Staggs,Aaron L. Sarver,Tracy L. Bergemann,Mihir Gupta,M. Gerard O'Sullivan,Ilze Matise,Adam J. Dupuy,Lara S. Collier,Scott Powers,Ann L. Oberg,Yan W. Asmann,Stephen N. Thibodeau,Lino Tessarollo,Neal G. Copeland,Nancy A. Jenkins,Robert T. Cormier,David A. Largaespada +19 more
TL;DR: A transposon-based genetic screen in mice identified 77 candidate CRC genes, 60 of which are mutated and/or dysregulated in human CRC and thus are most likely to drive tumorigenesis.