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Dennis C. Choi

Researcher at Emory University

Publications -  28
Citations -  4475

Dennis C. Choi is an academic researcher from Emory University. The author has contributed to research in topics: Stria terminalis & Chronic stress. The author has an hindex of 25, co-authored 28 publications receiving 4091 citations. Previous affiliations of Dennis C. Choi include University of Cincinnati & Vanderbilt University.

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Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness.

TL;DR: The principle extrinsic and intrinsic mechanisms responsible for regulating stress-responsive CRH neurons of the hypothalamic paraventricular nucleus, which summate excitatory and inhibitory inputs into a net secretory signal at the pituitary gland, are reviewed.
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Chronic stress induces adrenal hyperplasia and hypertrophy in a subregion-specific manner

TL;DR: Exogenous ACTH administration to dexamethasone-blocked rats demonstrated that CVS increased maximal plasma and adrenal corticosterone responses to ACTH without affecting sensitivity, and increased adrenal weight after CVS is due to hyperplasia and hypertrophy that occur in specific adrenal subregions and is associated with increased maximal cortic testosterone responses toACTH.
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Bed Nucleus of the Stria Terminalis Subregions Differentially Regulate Hypothalamic–Pituitary–Adrenal Axis Activity: Implications for the Integration of Limbic Inputs

TL;DR: The results indicate that the BST contains functional subdomains that play different roles in integrating and processing limbic information in response to stress and further suggest that excitatory as well as inhibitory limbic Information is funneled through these important cell groups.
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Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear

TL;DR: It is found that prelimbic BDNF is critical for consolidation of learned fear memories, but it is not required for innate fear or extinction of fear.
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Pleasurable behaviors reduce stress via brain reward pathways.

TL;DR: It is demonstrated that palatable food intake (limited intake of sucrose drink) reduces neuroendocrine, cardiovascular, and behavioral responses to stress in rats, and it is suggested that the palatable/rewarding properties of Sucrose are necessary and sufficient for stress dampening.