K
Kellie L.K. Tamashiro
Researcher at Johns Hopkins University School of Medicine
Publications - 113
Citations - 6391
Kellie L.K. Tamashiro is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Offspring & Social stress. The author has an hindex of 37, co-authored 106 publications receiving 5777 citations. Previous affiliations of Kellie L.K. Tamashiro include University of Hawaii at Manoa & University of Maryland, Baltimore.
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Journal ArticleDOI
Cloned mice have an obese phenotype not transmitted to their offspring
Kellie L.K. Tamashiro,Teruhiko Wakayama,Hidenori Akutsu,Yukiko Yamazaki,Jennifer Lachey,Matthew D. Wortman,Randy J. Seeley,David A. D'Alessio,Stephen C. Woods,Ryuzo Yanagimachi,Randall R. Sakai +10 more
TL;DR: It is reported that the increased body weight of cloned B6C3F1 female mice reflects an increase of body fat in addition to a larger body size, and that these mice share many characteristics consistent with obesity.
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Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
Mali Jiang,Jiawei Wang,Jiawei Wang,Jinrong Fu,Lin Du,Hyunkyung Jeong,Tim West,Lan Xiang,Qi Peng,Zhipeng Hou,Huan Cai,Tamara Seredenina,Nicolas Arbez,Shanshan Zhu,Katherine Sommers,Jennifer Qian,Jiangyang Zhang,Susumu Mori,X. William Yang,Kellie L.K. Tamashiro,Susan Aja,Timothy H. Moran,Ruth Luthi-Carter,Bronwen Martin,Stuart Maudsley,Mark P. Mattson,Robert H. Cichewicz,Christopher A. Ross,David M. Holtzman,Dimitri Krainc,Wenzhen Duan +30 more
TL;DR: Krainc et al. as mentioned in this paper showed that mutant HTT proteins in mice can bind and inactivate the deacetylase enzyme SIRT1 and that SIRT 1 overexpression is protective in Huntington's disease mouse models.
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Prenatal Stress or High Fat Diet increases Susceptibility to Diet-Induced Obesity in Rat Offspring
TL;DR: It is demonstrated that prenatal stress and/or high-fat diet during the intrauterine or postnatal environment affects offspring in a manner that increases their susceptibility to diet-induced obesity and leads to secondary adverse metabolic consequences.
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Chronic Corticosterone Exposure Increases Expression and Decreases Deoxyribonucleic Acid Methylation of Fkbp5 in Mice
Richard S. Lee,Kellie L.K. Tamashiro,Xiaoju Yang,Ryan H. Purcell,Amelia Harvey,Virginia L. Willour,Yuqing Huo,Michael Rongione,Gary S. Wand,James B. Potash +9 more
TL;DR: The results suggest DNAm plays a role in mediating effects of glucocorticoid exposure on Fkbp5 function, with potential consequences for behavior.
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Social stress: from rodents to primates.
TL;DR: This review provides an overview of common rodent and non-human primate models of social stress used in the laboratory with a focus on social hierarchy models and the implications on understanding of the development of stress-related disease.