D
Dennis E. Bullard
Researcher at Duke University
Publications - 74
Citations - 4115
Dennis E. Bullard is an academic researcher from Duke University. The author has contributed to research in topics: Glioma & Procarbazine. The author has an hindex of 32, co-authored 74 publications receiving 3835 citations. Previous affiliations of Dennis E. Bullard include University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma
Jan C. Buckner,Edward G. Shaw,Stephanie L. Pugh,Arnab Chakravarti,Mark R. Gilbert,Geoffrey R. Barger,Stephen W. Coons,Peter Ricci,Dennis E. Bullard,Paul D. Brown,Keith J. Stelzer,David Brachman,John H. Suh,Christopher J. Schultz,Jean Paul Bahary,Barbara Fisher,Barbara Fisher,Harold Kim,Albert Murtha,Erica Hlavin Bell,Minhee Won,Minesh P. Mehta,Walter J. Curran +22 more
TL;DR: In a cohort of patients with grade 2 glioma who were younger than 40 years of age and had undergone subtotal tumor resection or who were 40 yearsof age or older, progression-free survival and overall survival were longer among those who received combination chemotherapy in addition to radiation therapy than amongThose who received radiation therapy alone.
Journal Article
Specific Chromosomal Abnormalities in Malignant Human Gliomas
Sandra H. Bigner,Joachim Mark,Peter C. Burger,Mahaley Ms,Dennis E. Bullard,Lawrence H. Muhlbaier,Darell D. Bigner +6 more
TL;DR: This demonstration of specific chromosomal abnormalities in near-diploid gliomas provides the basis for the investigation of genes which may be quantitatively or qualitatively altered in these neoplasms.
Journal ArticleDOI
Recurrence following neurosurgeon-determined gross-total resection of adult supratentorial low-grade glioma: results of a prospective clinical trial: Clinical article
Edward G. Shaw,B. Berkey,Stephen W. Coons,Dennis E. Bullard,David Brachman,Jan C. Buckner,Keith J. Stelzer,Geoffrey R. Barger,Paul D. Brown,Mark R. Gilbert,Minesh P. Mehta +10 more
TL;DR: It is suggested that young adult patients with low-grade glioma who undergo a neurosurgeon-determined GTR have a > 50% risk of tumor progression 5-years postoperatively, warranting close follow-up and consideration for adjuvant treatment.
Journal ArticleDOI
Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines.
TL;DR: This model allows cell lines derived from human gliomas to be grown in animal hosts, thereby providing a potential means for evaluating growth parameters and chemotherapeutic responsiveness of tumors derived from individual humangliomas or cell lines.
Journal ArticleDOI
Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations.
TL;DR: It is shown that in addition to double minutes, certain other gross structural abnormalities also are clearly associated with the early evolution of this type of tumor.