S
Stephanie L. Pugh
Researcher at American College of Radiology
Publications - 127
Citations - 8011
Stephanie L. Pugh is an academic researcher from American College of Radiology. The author has contributed to research in topics: Medicine & Prostate cancer. The author has an hindex of 25, co-authored 99 publications receiving 5937 citations. Previous affiliations of Stephanie L. Pugh include Washington University in St. Louis & Radiation Therapy Oncology Group.
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Journal ArticleDOI
A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
Mark R. Gilbert,James J. Dignam,Terri S. Armstrong,Terri S. Armstrong,Jeffrey S. Wefel,Deborah T. Blumenthal,Michael A. Vogelbaum,Howard Colman,Arnab Chakravarti,Stephanie L. Pugh,Minhee Won,Robert Jeraj,Paul D. Brown,Kurt A. Jaeckle,David Schiff,Volker W. Stieber,David Brachman,Maria Werner-Wasik,Ivo W. Tremont-Lukats,Erik P. Sulman,Kenneth Aldape,Walter J. Curran,Minesh P. Mehta +22 more
TL;DR: First-line use of bevacizumab did not improve overall survival in patients with newly diagnosed glioblastoma, and progression-free survival was prolonged but did not reach the prespecified improvement target.
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Preservation of Memory With Conformal Avoidance of the Hippocampal Neural Stem-Cell Compartment During Whole-Brain Radiotherapy for Brain Metastases (RTOG 0933): A Phase II Multi-Institutional Trial
Vinai Gondi,Stephanie L. Pugh,Wolfgang A. Tomé,Chip Caine,Ben W Corn,Andrew A. Kanner,Howard A. Rowley,Vijayananda Kundapur,Albert S. DeNittis,Jeffrey Greenspoon,Andre Konski,Glenn Bauman,Sunjay Shah,Wenyin Shi,Merideth M Wendland,Lisa A. Kachnic,Minesh P. Mehta +16 more
TL;DR: Conformal avoidance of the hippocampus during WBRT is associated with preservation of memory and QOL as compared with historical series.
Journal ArticleDOI
Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial.
Paul D. Brown,Stephanie L. Pugh,Nadia N. Laack,Jeffrey S. Wefel,Deepak Khuntia,Christina A. Meyers,Ali Choucair,Sherry Fox,John H. Suh,David Roberge,V.S. Kavadi,Søren M. Bentzen,Minesh P. Mehta,Deborah Watkins-Bruner +13 more
TL;DR: Overall, patients treated with memantine had better cognitive function over time; specifically, memantine delayed time to cognitive decline and reduced the rate of decline in memory, executive function, and processing speed in patients receiving WBRT.
Journal ArticleDOI
Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma
Jan C. Buckner,Edward G. Shaw,Stephanie L. Pugh,Arnab Chakravarti,Mark R. Gilbert,Geoffrey R. Barger,Stephen W. Coons,Peter Ricci,Dennis E. Bullard,Paul D. Brown,Keith J. Stelzer,David Brachman,John H. Suh,Christopher J. Schultz,Jean Paul Bahary,Barbara Fisher,Barbara Fisher,Harold Kim,Albert Murtha,Erica Hlavin Bell,Minhee Won,Minesh P. Mehta,Walter J. Curran +22 more
TL;DR: In a cohort of patients with grade 2 glioma who were younger than 40 years of age and had undergone subtotal tumor resection or who were 40 yearsof age or older, progression-free survival and overall survival were longer among those who received combination chemotherapy in addition to radiation therapy than amongThose who received radiation therapy alone.
Journal ArticleDOI
Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer
William U. Shipley,W. Seiferheld,H. Lukka,Pierre Major,Niall M. Heney,David J. Grignon,Oliver Sartor,Maltibehn P. Patel,Jean Paul Bahary,Anthony L. Zietman,Thomas M. Pisansky,Kenneth L. Zeitzer,Colleen A. Lawton,Felix Y. Feng,Richard Dana Lovett,Alexander Balogh,Luis Souhami,Seth A. Rosenthal,Kevin J. Kerlin,James J. Dignam,Stephanie L. Pugh,Howard M. Sandler +21 more
TL;DR: The addition of 24 months of antiandrogen therapy with daily bicalutamide to salvage radiation therapy resulted in significantly higher rates of long‐term overall survival and lower incidences of metastatic prostate cancer and death from prostate cancer than radiation therapy plus placebo.