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Derek L. Buhl

Researcher at Pfizer

Publications -  32
Citations -  4616

Derek L. Buhl is an academic researcher from Pfizer. The author has contributed to research in topics: Hippocampus & Medicine. The author has an hindex of 17, co-authored 28 publications receiving 4112 citations. Previous affiliations of Derek L. Buhl include Massachusetts Institute of Technology & Rutgers University.

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Communication between neocortex and hippocampus during sleep in rodents

TL;DR: A robust correlation of neuronal discharges between the somatosensory cortex and hippocampus on both slow and fine time scales in the mouse and rat is shown, suggesting that oscillation-mediated temporal links coordinate specific information transfer between neocortical and hippocampal cell assemblies.
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Transgenic Inhibition of Synaptic Transmission Reveals Role of CA3 Output in Hippocampal Learning

TL;DR: A generally applicable tetanus toxin–based method for transgenic mice that permits inducible and reversible inhibition of synaptic transmission and applied it to the trisynaptic pathway is developed and it is found that synaptic output from CA3 in the transexual pathway is dispensable and the short monosynaptic pathways is sufficient for incremental spatial learning.
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Hippocampal network patterns of activity in the mouse

TL;DR: The electrical patterns in the behaving animal are investigated using multisite silicon probes and wire tetrodes and it is suggested that the main hippocampal network patterns are mediated by similar pathways and mechanisms in mouse and rat.