S
Svetlana Vronskaya
Researcher at Columbia University
Publications - 11
Citations - 3779
Svetlana Vronskaya is an academic researcher from Columbia University. The author has contributed to research in topics: Long-term potentiation & Synaptic plasticity. The author has an hindex of 11, co-authored 11 publications receiving 3571 citations. Previous affiliations of Svetlana Vronskaya include Howard Hughes Medical Institute.
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Journal ArticleDOI
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.
Juan Marcos Alarcon,Gaël Malleret,Khalid Touzani,Svetlana Vronskaya,Shunsuke Ishii,Eric R. Kandel,Eric R. Kandel,Angel Barco +7 more
TL;DR: Some of the cognitive and physiological deficits observed on RTS are not simply due to the reduction of CBP during development but may also result from the continued requirement throughout life for both the CREB co-activation and the histone acetylation function of CBp.
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Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning.
Christoph Kellendonk,Eleanor H. Simpson,H. Jonathan Polan,Gaël Malleret,Svetlana Vronskaya,Vanessa Winiger,Holly Moore,Eric R. Kandel +7 more
TL;DR: It is found that D2R overexpression in the striatum impacts dopamine levels, rates of dopamine turnover, and activation of D1 receptors in the prefrontal cortex, measures that are critical for working memory.
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Reversible Inhibition of CREB/ATF Transcription Factors in Region CA1 of the Dorsal Hippocampus Disrupts Hippocampus-Dependent Spatial Memory
Christopher Pittenger,Yan You Huang,Ronald F. Paletzki,Roussoudan Bourtchouladze,Heather Scanlin,Svetlana Vronskaya,Eric R. Kandel,Eric R. Kandel +7 more
TL;DR: These experiments represent the first targeting of the dorsal hippocampus in genetically modified mice and confirm a role for CREB in hippocampus-dependent learning and suggest that some experimental forms of plasticity bypass the requirement forCREB.
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A Behavioral Role for Dendritic Integration: HCN1 Channels Constrain Spatial Memory and Plasticity at Inputs to Distal Dendrites of CA1 Pyramidal Neurons
Matthew F. Nolan,Gaël Malleret,Josh T. Dudman,Derek L. Buhl,Bina Santoro,Emma Gibbs,Svetlana Vronskaya,György Buzsáki,Steven A. Siegelbaum,Eric R. Kandel,Alexei Morozov +10 more
TL;DR: It is suggested that HCN1 channels constrain learning and memory by regulating dendritic integration of distal synaptic inputs to pyramidal cells.
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Identification of a Signaling Network in Lateral Nucleus of Amygdala Important for Inhibiting Memory Specifically Related to Learned Fear
Gleb P. Shumyatsky,Evgeny Tsvetkov,Gaël Malleret,Svetlana Vronskaya,Michael Hatton,Lori L. Hampton,James F. Battey,Catherine Dulac,Eric R. Kandel,Vadim Y. Bolshakov +9 more
TL;DR: Genetic evidence is provided that GRP and its neural circuitry operate as a negative feedback regulating fear and establish a causal relationship between Grpr gene expression, LTP, and amygdala-dependent memory for fear.