D
Devapriya Choudhury
Researcher at Jawaharlal Nehru University
Publications - 40
Citations - 2069
Devapriya Choudhury is an academic researcher from Jawaharlal Nehru University. The author has contributed to research in topics: Bacterial adhesin & Chaperone (protein). The author has an hindex of 17, co-authored 37 publications receiving 1914 citations. Previous affiliations of Devapriya Choudhury include Vrije Universiteit Brussel & Swedish University of Agricultural Sciences.
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Journal ArticleDOI
X-ray Structure of the FimC-FimH Chaperone-Adhesin Complex from Uropathogenic Escherichia coli
Devapriya Choudhury,Andrew F. Thompson,Vivian Stojanoff,Solomon Langermann,Jerome S. Pinkner,Scott J. Hultgren,Stefan D. Knight +6 more
TL;DR: The x-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli at 2.5 angstrom resolution reveals the basis for carbohydrate recognition and for pilus assembly.
Journal ArticleDOI
Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin
Julie Bouckaert,Jenny Berglund,Mark A. Schembri,Erwin De Genst,Lieve Cools,Manfred Wuhrer,Chia-Suei Hung,Jerome S. Pinkner,Rikard Slättegård,Anton V. Zavialov,Devapriya Choudhury,Solomon Langermann,Scott J. Hultgren,Lode Wyns,Per Klemm,Stefan Oscarson,Stefan D. Knight,Henri De Greve +17 more
TL;DR: These relative FimH affinities correlate exceptionally well with the relative concentrations of the same glycans needed for the inhibition of adherence of type 1 piliated E. coli.
Journal ArticleDOI
Substrate binding site of naphthalene 1,2-dioxygenase: functional implications of indole binding.
Enrique Carredano,Andreas Karlsson,Björn Kauppi,Devapriya Choudhury,Rebecca E. Parales,Juanito V. Parales,Kyoung Lee,David T. Gibson,Hans Eklund,S. Ramaswamy +9 more
TL;DR: The three-dimensional structure of the aromatic hydroxylating enzyme naphthalene dioxygenase (NDO) from Pseudomonas sp.
Journal ArticleDOI
Chaperone-assisted pilus assembly and bacterial attachment
Frederic G. Sauer,Michelle M. Barnhart,Devapriya Choudhury,Stefan D. Knight,Gabriel Waksman,Scott J. Hultgren +5 more
TL;DR: Work has begun to reveal the structural basis both of chaperone function in the biogenesis of these pili and of bacterial attachment in the establishment of an infection.
Journal ArticleDOI
The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes.
Julie Bouckaert,Jenny Mackenzie,José L. de Paz,Beatrice Chipwaza,Devapriya Choudhury,Anton V. Zavialov,Karin Mannerstedt,Jennifer Anderson,Denis Pierard,Lode Wyns,Peter H. Seeberger,Stefan Oscarson,Henri De Greve,Stefan D. Knight +13 more
TL;DR: It is found that FimH variants from uropathogenic, faecal and enterohaemorrhagic isolates express the same specificities and affinities for high‐mannose structures and implies that the carbohydrate expression profile of targeted host tissues and of natural inhibitors in urine, such as Tamm‐Horsfall protein, are stronger determinants of adhesion than FIMH variation.